Results 21 to 30 of about 142,530 (222)

Large High-Efficiency Thermal Neutron Detectors Based on the Micromegas Technology

Universe, 2018
Due to the so-called 3He shortage crisis, many detection techniques for thermal neutrons are currently based on alternative converters. There are several possible ways of increasing the detection efficiency for thermal neutrons using the solid neutron-to-
Georgios Tsiledakis, Alain Delbart, Daniel Desforge, Ioanis Giomataris, Thomas Papaevangelou, Richard Hall-Wilton, Carina Höglund, Linda Robinson, Susann Schmidt, Alain Menelle, Michal Pomorski   +10 more
doaj   +1 more source

Combination therapy with a novel CD2-targeted costimulatory bispecific antibody overcomes limitations of CD3 T cell engager treatment for solid tumors

mAbs
CD3 T cell engagers (TCEs) have transformed hematologic oncology, but dose-liming toxicity and the absence of adequate costimulation have limited TCE success in solid tumors.
Welbeck Danquah, Mélanie Pichery, Thomas Eden, Aurelien Boyance, Lise Pasquet, Virginie Roure, Marion Mars, Alice Marchand, Ellen Gumz, Mylène Gador, Lou Valente, Marion Contini, Lukas Czernecki, Sanjith Shanmuganathan, Pauline Barron, Sophie Chabot, Markus Dangl, Gerhard Niederfellner   +17 more
doaj   +1 more source

ROOT-ExM: Super-Resolution Imaging of Proteins in Arabidopsis Roots by Expansion Microscopy

Bio-Protocol
Conventional light microscopy is limited in resolution by the diffraction limit of light, restricting the visualization of the nanoscale organization of biomolecules. Expansion microscopy (ExM) has emerged as a powerful technique to overcome this barrier
Yutaro Shimizu, Guillaume Maucort, Mónica Fernández-Monreal, Florentin Dumas, Emmanuelle Bayer, Yohann Boutté, Magali Grison   +6 more
doaj   +1 more source

TiVZrNb Multi-Principal-Element Alloy: Synthesis Optimization, Structural, and Hydrogen Sorption Properties

Molecules, 2019
While the overwhelming number of papers on multi-principal-element alloys (MPEAs) focus on the mechanical and microstructural properties, there has been growing interest in these alloys as solid-state hydrogen stores.
Jorge Montero, Claudia Zlotea, Gustav Ek, Jean-Claude Crivello, Lætitia Laversenne, Martin Sahlberg   +5 more
doaj   +1 more source

Three-dimensional structure and stability of discontinuities between unmagnetized pair plasma and magnetized electron-proton plasma

New Journal of Physics, 2023
We study with a 3D particle-in-cell simulation discontinuities between an electron–positron pair plasma and magnetized electrons and protons. A pair plasma is injected at one simulation boundary with a speed 0.6 c along its normal.
M E Dieckmann, D Folini, M Falk, A Bock, P Steneteg, R Walder   +5 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Advanced Robotics Research, EarlyView.
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix, Molly Carton, Olivia M. Young, Noah Barnes, Jordi T. Andreou, Sarah McHugh, Jack E. McCann, Claudia Davis, Victoria Reddig‐Leiman, Afsah Kamran, Dheeraj Gandhi, Miroslaw Janowski, Jeremy D. Brown, Mark Fuge, Axel Krieger, Clifford R. Weiss, Christopher R. Bailey, Ryan D. Sochol   +17 more
wiley   +1 more source

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta‐Analysis of the European Myeloma Network (EMN)

American Journal of Hematology, EarlyView.
Our meta‐analysis showed significant improvement of PFS with lenalidomide, proteasome inhibitors, and CD38‐based therapies. A significant OS benefit was noted only with lenalidomide in transplant‐eligible (TE) patients, while CD38‐directed therapy showed a trend toward improved OS.
Heinz Ludwig, Evangelos Terpos, Francesca Gay, Niels W. C. J. van de Donk, Sarah Bernhard, Monika Engelhardt, Gordon Cook, Fredrik Schjesvold, Hermann Einsele, Graham Jackson, Charlotte Pawlyn, María‐Victoria Mateos, Sonja Zweegman, Martin Schreder, Meral Beksaç, Christoph Driessen, Enrique M. Ocio, Rakesh Popat, Leo Rasche, Cyrille Touzeau, Pellegrino Musto, Annemiek Broijl, Meletios Dimopoulos, Roman Hajek, Mario Boccadoro, Pieter Sonneveld   +25 more
wiley   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Se garder de la tyrannie de la peste en France (XVIe-XVIIe siècles)

Acta Universitatis Lodziensis: Folia Litteraria Romanica, 2022
Prolongeant les recherches actuelles sur les pandémies en Europe et en particulier dans la France des XVIe et XVIIe siècles, nous nous sommes proposés d’examiner dans le présent article les recommandations médicales qui visaient à protéger les patients ...
Magdalena Koźluk
doaj   +1 more source