Results 21 to 30 of about 143,231 (228)

Large High-Efficiency Thermal Neutron Detectors Based on the Micromegas Technology

Universe, 2018
Due to the so-called 3He shortage crisis, many detection techniques for thermal neutrons are currently based on alternative converters. There are several possible ways of increasing the detection efficiency for thermal neutrons using the solid neutron-to-
Georgios Tsiledakis, Alain Delbart, Daniel Desforge, Ioanis Giomataris, Thomas Papaevangelou, Richard Hall-Wilton, Carina Höglund, Linda Robinson, Susann Schmidt, Alain Menelle, Michal Pomorski   +10 more
doaj   +1 more source

Combination therapy with a novel CD2-targeted costimulatory bispecific antibody overcomes limitations of CD3 T cell engager treatment for solid tumors

mAbs
CD3 T cell engagers (TCEs) have transformed hematologic oncology, but dose-liming toxicity and the absence of adequate costimulation have limited TCE success in solid tumors.
Welbeck Danquah, Mélanie Pichery, Thomas Eden, Aurelien Boyance, Lise Pasquet, Virginie Roure, Marion Mars, Alice Marchand, Ellen Gumz, Mylène Gador, Lou Valente, Marion Contini, Lukas Czernecki, Sanjith Shanmuganathan, Pauline Barron, Sophie Chabot, Markus Dangl, Gerhard Niederfellner   +17 more
doaj   +1 more source

ROOT-ExM: Super-Resolution Imaging of Proteins in Arabidopsis Roots by Expansion Microscopy

Bio-Protocol
Conventional light microscopy is limited in resolution by the diffraction limit of light, restricting the visualization of the nanoscale organization of biomolecules. Expansion microscopy (ExM) has emerged as a powerful technique to overcome this barrier
Yutaro Shimizu, Guillaume Maucort, Mónica Fernández-Monreal, Florentin Dumas, Emmanuelle Bayer, Yohann Boutté, Magali Grison   +6 more
doaj   +1 more source

TiVZrNb Multi-Principal-Element Alloy: Synthesis Optimization, Structural, and Hydrogen Sorption Properties

Molecules, 2019
While the overwhelming number of papers on multi-principal-element alloys (MPEAs) focus on the mechanical and microstructural properties, there has been growing interest in these alloys as solid-state hydrogen stores.
Jorge Montero, Claudia Zlotea, Gustav Ek, Jean-Claude Crivello, Lætitia Laversenne, Martin Sahlberg   +5 more
doaj   +1 more source

Three-dimensional structure and stability of discontinuities between unmagnetized pair plasma and magnetized electron-proton plasma

New Journal of Physics, 2023
We study with a 3D particle-in-cell simulation discontinuities between an electron–positron pair plasma and magnetized electrons and protons. A pair plasma is injected at one simulation boundary with a speed 0.6 c along its normal.
M E Dieckmann, D Folini, M Falk, A Bock, P Steneteg, R Walder   +5 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Preferential trading in agriculture: New insights from a structural gravity analysis and machine learning

American Journal of Agricultural Economics, EarlyView.
Abstract Preferential trade agreements (PTAs) contain various non‐tariff provisions, yet identifying their trade effects remains challenging because these commitments are high‐dimensional and strongly correlated within agreements. We estimated a theory‐consistent structural gravity model with domestic flows for 26 agricultural subsectors over 1988–2017
Dongin Kim, Sandro Steinbach
wiley   +1 more source

Eltrombopag Added to Standard Immunosuppressive Treatment as Front‐Line Therapy for Severe Aplastic Anemia: Long‐Term Outcomes of the Phase‐3 Randomized Superiority EBMT‐SAAWP RACE Study

American Journal of Hematology, EarlyView.
ABSTRACT The RACE study (NCT02009747) compared horse antithymocyte globulin (hATG) plus cyclosporine A (CsA) ± eltrombopag as initial immunosuppressive treatment (IST) for severe aplastic anemia. Here we report the final 2‐year analysis of this prospective randomized phase III study.
Antonio M. Risitano, Simona Iacobelli, Austin Kulasekararaj, Marleen van Os, Sofie R. Terwel, Joe Tuffnell, Brian Piepenbroek, Morag Griffin, Constantijn J. M. Halkes, Christian Recher, Fiorenza Barraco, Edouard Forcade, Juan Carlos Vallejo, Beatrice Drexler, Jean‐Baptiste Mear, Roochi Trikha, Shreyans Gandhi, Anna Maria Raiola, L. G. M. Daenen, Marco R. de Groot, Etienne Daguindau, Erfan Nur, Wilma Barcellini, Nigel H. Russell, Louis Terriou, Anna Paola Iori, Walter Barberi, Anna Sureda, Isabel Sánchez‐Ortega, Blanca Xicoy, Isidro Jarque, James Cavenagh, Flore Sicre de Fontbrune, Camilla Frieri, Talha Munir, Jennifer M. L. Tjon, Suzanne Tavitian, Aline Praire, Laurence Clement, Florence Rabian, Luana Marano, Anita Hill, Elena Palmisani, Petra Muus, Serena Marotta, Fabiana Cacace, Marica Laurino, Jakob R. Passweg, Gérard Socié, Ghulam J. Mufti, Carlo Dufour, Régis Peffault de Latour, Severe Aplastic Anaemia Working Party of the EBMT   +52 more
wiley   +1 more source

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Evaluation of the impact of a Herd Health and Production Management programme in organic dairy cattle farms: a process evaluation approach

Animal, 2018
Animal health planning activities are not always providing a satisfactory positive impact on herd health and welfare. Moreover, evaluating the impact of advisory programmes is complex due to multiple interacting elements that influence its outcome ...
J.E. Duval, N. Bareille, A. Madouasse, M. de Joybert, K. Sjöström, U. Emanuelson, F. Bonnet-Beaugrand, C. Fourichon   +7 more
doaj   +1 more source