Results 171 to 180 of about 5,354,916 (300)

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

Advanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne, Julian S. Hertel, André Delavault, Judith Felk, Martin Peng, Lara Reuber, Felix Ott, Kim Wanner, Marc F. Münker, Adrian Neukirch, Alexei Kiselev, Kersten S. Rabe, Christof M. Niemeyer   +12 more
wiley   +1 more source

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

Advanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang, Jerry Leung, Judy Cheng, Arash Momeni, Albert Kamanzi, Ariadne Tuckmantel Bido, Suiyang Liao, Emma Kang, Colton Strong, Christian J. Kastrup, Sabrina Leslie, Miffy Hok Yan Cheng, Pieter R. Cullis   +12 more
wiley   +1 more source

Directional Confinement Governed Ion Transport for Efficient Actuation

Advanced Materials, EarlyView.
Structural anisotropy provides an effective means to regulate ion transport in polymer electrolytes. Directionally aligned channels formed by freeze‐drying provide continuous pathways for ion migration, enhancing ion mobility and simultaneously improving the strain and blocking force of ionic actuators.
Yufei Zhang, Qiuchun Lu, Adit Gupta, Sen Wang, Xueyang Wang, Jian Yu, Xuanyi Hu, Daniel Mandler, Pooi See Lee   +8 more
wiley   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source

Dual Single Atoms Boosting Photocatalytic Upcycling of Raw Polyvinylidene Fluoride Plastic

Advanced Materials, EarlyView.
To resolve the catastrophic disaster of plastic contamination, the Cu‐Fe dual‐single‐atom‐loaded In2P3S9 NSs photocatalyst was prepared for direct conversion of raw polyvinylidene fluoride plastic into valuable chemicals. The dual‐single‐atom catalyst exhibits exceptional performance, with a total acetic/formic acid production of ∼1351.8 µmol g−1 ...
Amin Talebian‐Kiakalaieh, Shiying Ren, Wenzhong Ji, Yun Liu, Bingquan Xia, Jingrun Ran, Shi‐Zhang Qiao   +6 more
wiley   +1 more source

Can a simple geoengineering approach restore dwindling Arctic ice? [PDF]

Proc Natl Acad Sci U S A
Irfan U.
europepmc   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Polar and subpolar shelf seas dominate enhanced coastal CO₂ uptake during marine heatwaves. [PDF]

Nat Commun
Hu Z, Mathis M, Li H, Ilyina T, Voynova YG, Macovei VA, Zhou F, Meng Q, Schrum C, Zhang W.   +9 more
europepmc   +1 more source

Near‐Infrared Imaging of H2O2 in Plants With Nanosensors Under Environmentally Changing Conditions

Advanced Materials, EarlyView.
This paper reports a ratiometric nanosensor enabling robust, multivariate detection of stress signals (H2O2) in plants, with high resistance to light fluctuations and mechanical disturbances. Single‐walled carbon nanotubes serve as the sensor, Egyptian Blue nanosheets serve as a stable reference, and plant autofluorescence serves as a label‐free ...
Jiaqi Li, Bjoern F. Hill, Chen Ma, Juliana Gretz, Tanuja Kistwal, Janus A. C. Wartmann, Justus T. Metternich, Juan Pablo Giraldo, Sebastian Kruss   +8 more
wiley   +1 more source

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source