Results 91 to 100 of about 947,730 (299)

Envisioning sea level rise in Golden Gate National Recreation Area [PDF]

open access: yes, 2020
A step-by-step explanation of how Golden Gate National Recreation Area developed a set of complementary climate change exhibits for various sites in the park, focused on the impacts of sea level ...
Castellini, Laura   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

SEA LEVEL RISE AND EQUITY WEIGHTING [PDF]

open access: yes
Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of national socio-economic scenarios.
David Anthoff   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Economic Impact of Substantial Sea-Level Rise [PDF]

open access: yes
Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of socio-economic scenarios downscaled to the national level, including the four SRES storylines.
David Anthoff   +3 more
core  

Impacts of sea-level rise-induced erosion on the Catalan coast [PDF]

open access: yes, 2017
The final publication is available at Springer via http://dx.doi.org/10.1007/s10113-016-1052-xThe Catalan coast as most of the developed Mediterranean coastal zone is characterized by the coincidence of stresses and pressures on the natural system with a
Bosom García, Eva   +4 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Atlantic meridional overturning circulation stable over the last 150 years

open access: yesQuaestiones Geographicae, 2019
The Atlantic Meridional Overturning Circulation (AMOC) describes the northward flow of warm, salty water in the upper layers, and the southward flow of colder water in the deep Atlantic layers.
Parker Albert, Ollier Clifford
doaj   +1 more source

SPATIAL ANALYSIS AS TOOL FOR SENSITIVITY ASSESSMENT OF SEA LEVEL RISE IMPACTS ON MARTINIQUE [PDF]

open access: yes
Sea level in the Caribbean region is expected to rise approximately10-20 cm by 2025. In some areas of Martinique coastal erosion and saltwater intrusion are already a severe problem.
Christine Schleupner
core  

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