Results 41 to 50 of about 1,689,783 (269)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang   +18 more
wiley   +1 more source

Analysis of amplitude statistical and correlation characteristics of high grazing angle sea-clutter

open access: yesThe Journal of Engineering, 2019
Research on the characteristics of sea clutter has always been the focus in the problem of sea target detection as an indispensable part. In recent years, the problem of sea clutter characteristics under medium-high grazing angle is also paid more and ...
Heng-Yan Liu   +5 more
doaj   +1 more source

Radar Clutter Backscattering Simulation for Specific Sites [PDF]

open access: yes, 2007
The state of development of the surface clutter prediction model DORTE is presented. This simulation program utilizes Digital Elevation Models and land use information to calculate reflectivity maps for specific sites with optional statistical variation ...
Rode, Gerald
core  

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

open access: yesAdvanced Materials, EarlyView.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko   +2 more
wiley   +1 more source

Esterified Cholesterol Conjugates Enable LNP‐Mediated mRNA Delivery to the Blood–Brain Barrier Following Intravenous Administration

open access: yesAdvanced Materials, EarlyView.
A cholesterol‐conjugated lipid library enabled the identification of a ligand‐free LNP platform for efficient mRNA delivery to brain endothelial cells via systemic administration. This platform achieves selective BBB targeting without disrupting barrier integrity, and enables modulation of neuroinflammation and vascular function without requiring trans‐
Zeru Tian   +7 more
wiley   +1 more source

Multiobjective Codesign Optimization of a Planar Pneumatic Artificial Muscle‐Based Snake‐Like Robot for Enhanced Agility and Energy Efficiency

open access: yesAdvanced Robotics Research, EarlyView.
A codesign multiobjective optimization framework was developed to enhance the morphology and controller of a snake‐like robot driven by artificial muscles. It improved planar locomotion, agility, and power efficiency. The approach optimized link geometry and controller gains, revealing that shorter muscles near joints and longer linkages maximize ...
Ayla Valles, Mahdi Haghshenas‐Jaryani
wiley   +1 more source

Small Target Detection in Sea Clutter Background Based on Tsallis Entropy of Doppler Spectrum

open access: yesLeida xuebao, 2019
According to the different concentration levels of Doppler spectrum between sea clutter and target, small target in sea clutter background can be detected using Shannon entropy.
CHEN Shichao   +3 more
doaj   +1 more source

Collision‐Resilient Winged Drones Enabled by Tensegrity Structures

open access: yesAdvanced Robotics Research, EarlyView.
Based on structures of birds such as the woodpeck, this article presents the collision‐resilient aerial robot, SWIFT. SWIFT leverages tensegrity structures in the fuselage and wings which allow it to undergo large deformations in a crash, without sustaining damage. Experiments show that SWIFT can reduce impact forces by 70% over conventional structures.
Omar Aloui   +5 more
wiley   +1 more source

An airborne radar sea clutter spectrum parameters estimation method based on intelligent learning

open access: yesXibei Gongye Daxue Xuebao
Traditional airborne radar sea clutter suppression methods have a high degree of human participation and large errors in estimating the clutter power spectrum.
FAN Yifei   +5 more
doaj   +1 more source

Multimodal Locomotion in Insect‐Inspired Microrobots: A Review of Strategies for Aerial, Surface, Aquatic, and Interfacial Motion

open access: yesAdvanced Robotics Research, EarlyView.
This review identifies key design considerations for insect‐inspired microrobots capable of multimodal locomotion. To draw inspiration, biological and robotic strategies for moving in air, on water surfaces, and underwater are examined, along with approaches for crossing the air–water interface.
Mija Jovchevska   +2 more
wiley   +1 more source

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