Results 191 to 200 of about 12,913 (258)

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Record-breaking Greenland ice sheet melt events under recent and future climate. [PDF]

Nat Commun
Bonsoms J, González-Herrero S, Fettweis X, Lemus-Cánovas M, Oliva M, López-Moreno JI.   +5 more
europepmc   +1 more source

Sunscreen‐Inspired Nano‐Pesticide for UV‐Shielding and Laccase‐Responsive Delivery of Mancozeb With Enhanced Fungicidal Efficacy and Ecological Safety

Advanced Science, EarlyView.
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan, Xin Ye, Linping He, Cheng Hong, Xu‐Huan Zhao, Gizachew Mulugeta Manahelohe, Xiao‐Tong Feng, Yu‐Cheng Gu, Qiang Bian, Min Wu, Ming‐Zhi Zhang   +10 more
wiley   +1 more source

Cascading continental-scale floods across Europe in 1342-1343. [PDF]

Nature
Kiss A, Viglione A, Barriendos M, Enzi S, Bauch M, Decker K, Maughan N, Retsö D, Ogilvie A, Bertola M, Soens T, Elleder L, Brázdil R, Pribyl K, Parajka J, Telelis I, Amorim I, Barriendos J, Böhm O, Benito G, Bertolin C, Camuffo D, Coeur D, Demarée G, Doktor R, Dotterweich M, Glaser R, Komma J, Macdonald N, Petrić H, Rohr C, Schmocker-Fackel P, Schulte L, Toonen WHJ, Wetter O, Blöschl G.   +35 more
europepmc   +1 more source

Rainfall Shapes the Diversity of Soil Nitrogen‐Fixing Microorganisms Worldwide

Advanced Science, EarlyView.
This study reveals the distinctive pattern and mechanism of rainfall driving the global biodiversity and biogeography of soil potential N‐fixing microorganisms, and constructs the theoretical framework. The results guide us on how to maintain ecosystem productivity under future climate changes (e.g., whether a specific region needs more N fertilizers ...
Bin Hua, Shuang Pang, Ang Li, Zonghao Hu, Honghui Wu, Shuhan Zhang, Yi Fan, Yi Wu, Wei Yang, Yachao Zhao, Yupeng Guan, Baoming Ji, Deliang Kong, Yong Zhao, Anton A. Goncharov, Anastasia Yu. Korotkevich, Rong Mao, Yang Zhang, Ximei Zhang   +18 more
wiley   +1 more source

Comparative genomics of an Antarctic sea-ice diatom (<i>Nitzschia</i> sp.) provides insights into potential polar adaptation. [PDF]

Front Microbiol
Zhai C, Kennedy F, Han M, Yu H, Sun J, Liang Y, Wang M, McMinn A.   +7 more
europepmc   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

Retracing the Response of Rangifer to Postglacial Climate Change in Arctic Islands. [PDF]

Ecol Evol
Dance M, Saupe EE, Farnsworth A, Valdes PJ, Macias-Fauria M.   +4 more
europepmc   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source

Benthic foraminiferal colonisation of phytodetritus during spring bloom within the marginal sea ice zone off Northern Svalbard continental margin. [PDF]

Sci Rep
Faizieva K, Wollenburg JE, Nagy M, Berndt C, Heinz P.   +4 more
europepmc   +1 more source