Results 41 to 50 of about 12,913 (258)
Simulated compact polarimetry from the RADARSAT Constellation Mission (RCM) is evaluated for sea ice classification. Compared to previous studies that evaluated the potential of RCM for sea ice classification, this study focuses on the High Resolution ...
Mohammed Dabboor +2 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Sea ice classification using multi-frequency polarimetric SAR data [PDF]
This paper discusses the capability of the complex Wishart classifier for sea ice and classification using multifrequency, fully polarimetric SAR data. C-, L-, and P-band data acquired by the JPL AIRSAR in the Beaufort Sea was used. Classification using the unsupervised Wishart classifier is a two-stage process. An initial classification is required to
Scheuchl, B., Hajnsek, I., Cumming, I.G.
openaire +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Sea ice type classification in the Chukchi sea using deep learning
This poster is prepared for the annual EarthCube meeting, 2021.
Vahedi, Behzad +6 more
openaire +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
NASA's Ice, Cloud, and Land Elevation Satellite‐2 (ICESat‐2) mission launched in September 2018 and is now providing high‐resolution surface elevation profiling across the entire globe, including the sea ice cover of the Arctic and Southern Oceans.
A. A. Petty +7 more
doaj +1 more source
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source

