Results 151 to 160 of about 471,351 (368)

Under-ice phytoplankton blooms inhibited by spring convective mixing in refreezing leads [PDF]

open access: yes, 2018
Author Posting. © American Geophysical Union, 2018. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution.
Arrigo, Kevin R.   +11 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Pan-Arctic sea ice concentration from SAR and passive microwave [PDF]

open access: yesThe Cryosphere
Arctic sea ice monitoring is a fundamental prerequisite for anticipating and mitigating the impacts of climate change. Satellite-based sea ice observations have been subject to intense attention over the last few decades, with passive microwave (PMW ...
T. Wulf   +4 more
doaj   +1 more source

EOF analysis of three records of sea-ice concentration spanning the last 30 years [PDF]

open access: yes, 2003
Several continuous observational datasets of Artic sea-ice concentration are currently available that cover the period since the advent of routine satellite observations. We report on a comparison of three sea-ice concentration datasets.
Comiso   +8 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

AARI methodology for sea ice charts composition

open access: yesРоссийская Арктика, 2019
Sea ice charts of the Arctic and Antarctic Research Institute (AARI) are widely used nowadays for a variety of scientific and practical tasks. However, detailed description of ice charts composition still has not been published.
E.V. Afanasyeva   +6 more
doaj   +1 more source

Impact of Daily Arctic Sea Ice Variability in CAM3.0 during Fall and Winter [PDF]

open access: yes, 2013
Climate projections suggest that an ice-free summer Arctic Ocean is possible within several decades and with this comes the prospect of increased ship traffic and safety concerns.
Bhatt, Uma S.   +4 more
core  

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

open access: yesFEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu   +8 more
wiley   +1 more source

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