Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić+9 more
wiley +1 more source
Evaluation of the ArcIOPS sea ice forecasts during 2021–2023
The operational sea ice forecasts from the Arctic Ice Ocean Prediction System (ArcIOPS) during 2021–2023 are validated against satellite-retrieved sea ice concentration and drift data, in situ and reanalyzed sea ice thickness data.
Xi Liang+5 more
doaj +1 more source
Impacts of Sea Ice Thickness Initialization on Seasonal Arctic Sea Ice Predictions
Abstract A promising means for increasing skill of seasonal predictions of Arctic sea ice is improving sea ice thickness (SIT) initial conditions; however, sparse SIT observations limit this potential. Using the Canadian Climate Model, version 3 (CanCM3), three statistical models designed to estimate SIT fields for initialization in a ...
Arlan Dirkson+2 more
openaire +2 more sources
An assessment of the Arctic Ocean in a suite of interannual CORE-II simulations. Part I: Sea ice and solid freshwater [PDF]
The Arctic Ocean simulated in fourteen global ocean-sea ice models in the framework of the Coordinated Ocean-ice Reference Experiments, phase II (CORE II) is analyzed. The focus is on the Arctic sea ice extent, the solid freshwater (FW) sources and solid
Aagaard+95 more
core +2 more sources
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer+10 more
wiley +1 more source
Suitability of the CICE sea ice model for seasonal prediction and positive impact of CryoSat-2 ice thickness initialization [PDF]
The Los Alamos Community Ice CodE (CICE) sea ice model is being tested in standalone mode to identify biases that limit its suitability for seasonal prediction, where it is driven by atmospheric forcings from the NCEP Climate Forecast System Reanalysis ...
S. Sun, A. Solomon
doaj +1 more source
A multithickness sea ice model accounting for sliding friction [PDF]
A multithickness sea ice model explicitly accounting for the ridging and sliding friction contributions to sea ice stress is developed. Both ridging and sliding contributions depend on the deformation type through functions adopted from the Ukita and ...
Alexander V. Wilchinsky+38 more
core +2 more sources
1D Light‐Emitting MAPbBr3 Perovskite Encapsulated in Carbon Nanotubes
Encapsulation of MAPbBr3 perovskite in single‐walled carbon nanotubes (SWCNTs) yields a hybrid nanomaterial with distinctive optoelectronic properties. Perovskite confinement induces a unified single‐peak photoluminescence (PL) with a reduced lifetime, while charge transfer alters the optical properties of nanotubes.
Valentina A. Eremina+7 more
wiley +1 more source
A Modeling Experiment on the Grounding of an Ice Shelf in the Central Arctic Ocean During MIS 6 [PDF]
High-resolution chirp sonar subbottom profiles from the Lomonosov Ridge in the central Arctic Ocean, acquired from the Swedish icebreaker Oden in 1996, revealed large-scale erosion of the ridge crest down to depths of 1000 m below present sea level ...
Jakobsson, Martin+2 more
core +2 more sources
Eco‐friendly nanowave‐textured implants produced via femtosecond laser fabrication enhance bone regeneration by orchestrating a precise mechanotransduction cascade. This nanotopography directs mesenchymal stem cell alignment and cytoskeletal organization, triggering changes in nuclear shape and chromatin acetylation that prime cells for osteogenesis ...
Bosu Jeong+15 more
wiley +1 more source