Results 81 to 90 of about 176,859 (335)

Sea ice thickness estimated from passive microwave radiometers [PDF]

open access: yes, 2002
This study presents the findings of research into the correlation between sea ice thickness and passive microwave radiation. In-situ sea ice thickness samples were obtained from video observations by the icebreaker Soya during 1996-1998 and surface ...
Hiroyuki Enomoto   +3 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Relating the Age of Arctic Sea Ice to its Thickness, as Measured during NASA’s ICESat and IceBridge Campaigns

open access: yesRemote Sensing, 2016
Recent satellite observations yield estimates of the distribution of sea ice thickness across the entire Arctic Ocean. While these sensors were only placed in operation within the last few years, information from other sensors may assist us with ...
Mark A. Tschudi   +2 more
doaj   +1 more source

On the nature of the sea ice albedo feedback in simple models [PDF]

open access: yes, 2013
We examine the nature of the ice-albedo feedback in a long standing approach used in the dynamic-thermodynamic modeling of sea ice. The central issue examined is how the evolution of the ice area is treated when modeling a partial ice cover using a two-category-thickness scheme; thin sea ice and open water in one category and "thick" sea ice in the ...
arxiv   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Better constraints on the sea-ice state using global sea-ice data assimilation [PDF]

open access: yesGeoscientific Model Development, 2012
Short-term and decadal sea-ice prediction systems need a realistic initial state, generally obtained using ice–ocean model simulations with data assimilation. However, only sea-ice concentration and velocity data are currently assimilated.
P. Mathiot   +5 more
doaj   +1 more source

SAR image wave spectra to retrieve the thickness of grease-pancake sea ice using viscous wave models [PDF]

open access: yesarXiv, 2020
Young sea ice composed of grease and pancake ice (GPI), as well as thin floes, considered to be the most common form of sea ice fringing Antarctica, is now becoming the 'new normal' also in the Arctic. Investigations to determine how an increase in GPI is affecting the climate in the far north and globally, require specific tools to monitor the GPI's ...
arxiv  

Incorporating dependence on ice thickness in empirical parameterizations of wave dissipation by sea ice [PDF]

open access: yesarXiv, 2021
This study is part of an effort to improve the Navy's ability to forecast wind-generated ocean waves in ice-infested regions, and here we are attempting to further this goal by improving prediction of dissipation of wave energy by sea ice. Rogers et al.
arxiv  

Sea-ice thickness from field measurements in the northwestern Barents Sea [PDF]

open access: yesJournal of Geophysical Research: Oceans, 2017
The Barents Sea is one of the fastest changing regions of the Arctic, and has experienced the strongest decline in winter-time sea-ice area in the Arctic, at -23 +/- 4% per decade. Sea-ice thickness in the Barents Sea is not well studied. We present two previously unpublished helicopter-borne electromagnetic (HEM) ice thickness measurements from the ...
Caixin Wang   +7 more
openaire   +2 more sources

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

open access: yesFEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa   +13 more
wiley   +1 more source

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