Results 61 to 70 of about 2,824,835 (249)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Seasonal and Interannual Variations in Sea Ice Thickness in the Weddell Sea, Antarctica (2019–2022) Using ICESat-2

Remote Sensing
The sea ice extent in the Weddell Sea exhibited a positive trend from the start of satellite observations in 1978 until 2016 but has shown a decreasing trend since then.
Mansi Joshi, Alberto M. Mestas-Nuñez, Stephen F. Ackley, Stefanie Arndt, Grant J. Macdonald, Christian Haas   +5 more
doaj   +1 more source

An Improved Algorithm for the Retrieval of the Antarctic Sea Ice Freeboard and Thickness from ICESat-2 Altimeter Data

Remote Sensing, 2022
ICESat-2 altimeter data could be used to estimate sea ice freeboard and thickness values with a higher measuring accuracy than that achievable with data provided by previous altimeter satellites.
Xiaoping Pang, Yizhuo Chen, Qing Ji, Guoyuan Li, Lijian Shi, Musheng Lan, Zeyu Liang   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A weekly Arctic sea-ice thickness data record from merged CryoSat-2 and SMOS satellite data [PDF]

The Cryosphere, 2017
Sea-ice thickness on a global scale is derived from different satellite sensors using independent retrieval methods. Due to the sensor and orbit characteristics, such satellite retrievals differ in spatial and temporal resolution as well as in the ...
R. Ricker, R. Ricker, S. Hendricks, L. Kaleschke, X. Tian-Kunze, J. King, C. Haas, C. Haas   +7 more
doaj   +1 more source

Sea-ice thickness, snow depth, freeboard, scattering layer thickness, and sea-ice type at sea ice station PS78/230-1

, 2012
Sea-ice thickness, snow depth, freeboard, scattering layer thickness, and sea-ice type at sea ice station PS78/267-
James A Maslanik (6979643), Maslanik, James A, Nicolaus, Marcel, Christian Katlein (6962774), Stefan Hendricks (6887366), Hendricks, Stefan, Katlein, Christian, Marcel Nicolaus (6887372)   +7 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Relating the Age of Arctic Sea Ice to its Thickness, as Measured during NASA’s ICESat and IceBridge Campaigns

Remote Sensing, 2016
Recent satellite observations yield estimates of the distribution of sea ice thickness across the entire Arctic Ocean. While these sensors were only placed in operation within the last few years, information from other sensors may assist us with ...
Mark A. Tschudi, Julienne C. Stroeve, J. Scott Stewart   +2 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Sea ice thickness as a stochastic process [PDF]

Journal of Geophysical Research: Oceans, 2000
Observed probability distributions of sea ice thickness are approximately exponential for thick ice. An explanation is given on the basis of simple representations of the thermal and mechanical processes. The argument predicts that the e‐folding scale for the exponential is proportional to the thermal equilibrium thickness.
openaire   +1 more source