Results 171 to 180 of about 10,968,209 (307)

Forecasting compound sea level extremes: the 29-30 October 2018 Adriatic storm surge and meteotsunami extreme. [PDF]

Nat Hazards (Dordr)
Ruić K, Šepić J, Telišman Prtenjak M, Horvath K, Kvakić M.   +4 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Building Techno-Scientific Trust in Adaptation to Sea-Level Rise in the Dutch Online Media. [PDF]

Environ Manage
Bontenbal I, Husu HM.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Resolving short-term meteorological variability amplifies projected glacier loss and sea-level rise. [PDF]

Nat Commun
Van Tricht L, Huss M, Zekollari H, Aguayo R, Beer J, van Tiel M, von der Esch A, Farinotti D.   +7 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Sub-basin sea level budget analysis in the North Indian Ocean (2003-2024). [PDF]

Sci Rep
Pillai UM, Ghomsi FEK, Kochuparampil AJ, Raj RP, Johannessen OM.   +4 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Confluence : Spring/Summer 2018 - accessible version

Confluence is a newsletter of Oregon Sea Grant.
Oregon State University. Sea Grant College Program
core   +2 more sources

Observed thresholds in sea-level rise driving global tidal wetland loss. [PDF]

Nat Commun
Luo J, Hardi A, Dai Z, Nijland W, Mei X, Wang J, Nienhuis JH.   +6 more
europepmc   +1 more source