Results 131 to 140 of about 11,361,096 (291)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Cretaceous sea level rise : down memory lane and the road ahead /
Cretaceous Sea Level Rise delves into the question of whether the observed short-term sea-level changes are regional (tectonic) or global (eustatic) and determines their possible relation to climate cycles; to assess the role of feedback mechanisms, i.e.
Ramkumar, Mu,author.
core
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Sea Level Rise in Egypt's Nile River Delta: Policy Recommendations to Address Agricultural Decline and Infrastructural Damage [PDF]
, 2020 In this thesis, I evaluate the effects of sea level rise on agriculture and infrastructure in Egypt’s Nile River Delta. In response to these effects, I propose policy recommendations to adapt to sea level rise and ultimately mitigate agricultural decline
Hayes, Moriah
core
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Sea level rise in the Baltic Sea: Data from Estonian coastal tide gauges over 30 years
Geodesy and GeodynamicsThis study investigates the rate of sea level rise along the Estonian coastline of the Baltic Sea over the three decades (1993–2022) using tide gauge data and advanced analytical methods.
Ivar Kapsi, Tarmo Kall, Aive Liibusk
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
The impact of sea level rise on developing countries : a comparative analysis [PDF]
Sea level rise (SLR) due to climate change is a serious global threat. The scientific evidence is now overwhelming. Continued growth of greenhouse gas emissions and associated global warming could well promote SLR of 1m-3m in this century, and ...
Dasgupta, Susmita +4 more
core