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The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Deep Uncertainty Surrounding Coastal Flood Risk Projections: A Case Study for New Orleans

, 2017
Future sea-level rise drives severe risks for many coastal communities. Strategies to manage these risks hinge on a sound characterization of the uncertainties. For example, recent studies suggest that large fractions of the Antarctic ice sheet (AIS) may
Keller, Klaus, Wong, Tony E.
core   +1 more source

Global Dataset of Extreme Sea Levels and Coastal Flood Impacts over the 21st Century

Data
A global database of coastal flooding impacts resulting from extreme sea levels is developed for the present day and for the years 2050 and 2100. The database consists of three sub-datasets: the extreme sea levels, the coastal areas flooded by these ...
Ebru Kirezci, Ian Young, Roshanka Ranasinghe, Yiqun Chen, Yibo Zhang, Abbas Rajabifard   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Analysis of Abnormal Sea Level Rise in Offshore Waters of Bohai Sea in 2024

Journal of Marine Science and Engineering
The primary contribution of this study lies in analyzing the dynamic drivers during two anomalous sea level rise events in the Bohai Sea through coupled numeric modeling using the Weather Research and Forecasting (WRF) model and the Finite-Volume ...
Song Pan, Lu Liu, Yuyi Hu, Jie Zhang, Yongjun Jia, Weizeng Shao   +5 more
doaj   +1 more source

Chapter 12: Sea Level Rise [PDF]

Global mean sea level (GMSL) has risen by about 7-8 inches (about 16-21 cm) since 1900, with about 3 of those inches (about 7 cm) occurring since 1993. Human-caused climate change has made a substantial contribution to GMSL rise since 1900, contributing ...
Horton, R., Kopp, R. E., LeGrande, A. N., Romanou, A., Sweet, W. V.   +4 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Improving reporting of uncertainties in sea level rise assessments [PDF]

, 2010
Sea level rise (SLR) assessments are commonly used to identify the extent that coastal populations are at risk to flooding. However, the data and assumptions used to develop these assessments contain numerous sources and types of uncertainty, which ...
Kettle, Nathan
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source