Results 111 to 120 of about 947,492 (301)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
ECONOMY-WIDE ESTIMATES OF THE IMPLICATIONS OF CLIMATE CHANGE: SEA LEVEL RISE [PDF]
The economy-wide implications of sea level rise in 2050 are estimated using a static computable general equilibrium model. Overall, general equilibrium effects increase the costs of sea level rise, but not necessarily in every sector or region.
Francesco Bosello +2 more
core +3 more sources
Marine Law Symposium at RWU Law to Focus on Legal Strategies for Climate Adaptation [PDF]
, 2018 Nov. 16 event will be part of RWU’s yearlong series, “Ocean State/State of the Ocean: The Challenge of Sea-Level Rise Over the Coming Century”
Fitzpatrick, Edward
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2008 Here we present a set of regional climate scenarios of sea level rise for the northeast Atlantic Ocean. In this study, the latest observations and results obtained with state-of-the-art climate models are combined.
Burgers, Gerrit +4 more
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Downstream Hydrology Reduces Glaciers' Direct Contribution to Sea‐Level Rise
Geophysical Research LettersGlacier mass loss is a primary contributor to sea‐level rise. All prior assessments assume all glacial melt water reaches the ocean, but many mountain glaciers are located far from oceans and may be affected by the downstream systems.
David R. Rounce +7 more
doaj +1 more source
ASSESSING THE RISKS OF A FUTURE RAPID LARGE SEA LEVEL RISE: A REVIEW [PDF]
Our aim is to make an appropriate characterization and interpretation of the risk problem of rapid large sea level rise that reflects the very large uncertainty in present day knowledge concerning this possibility, and that will be useful in informing ...
Clark L. Goble +2 more
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