Results 181 to 190 of about 7,784 (254)

High-Throughput Sequencing Reveals Regional Diversification of Cucurbit-Infecting Begomoviruses in Eastern Saudi Arabia. [PDF]

Viruses
Sattar MN, Al Hashedi SA, Almaghasla MI, El-Ganainy SM, Al-Shoaibi AA, Munir M.   +5 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

The unmet need for the mitigation of snakebite envenoming in India: a one health perspective. [PDF]

Trop Med Health
Allen S, Munshi H, Chakma JK.
europepmc   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, EarlyView.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source

Surface Topography and Ultrastructure of the Spectacular Cells in the Eyes of Land and Sea Snakes (Squamata, Reptilia): Functional Adaptations of Micro-Ornamentation. [PDF]

J Morphol
Collin HB, Ha MH, Wagner A, Folwell M, Dunstan N, Crowe-Riddell J, Collin SP.   +6 more
europepmc   +1 more source

Basis Networks: Learning basis functions for free‐form triangulations

Computer Graphics Forum, EarlyView.
Abstract We present a framework for learning compactly supported basis functions that define tangent continuous surfaces based on coarse irregular triangle meshes. The basis functions are represented as MLPs. Smoothness of the basis functions is achieved by using the values of Loop basis functions as the parameterization of the surface.
T. Djuren, M. Alexa
wiley   +1 more source

Snakebite envenoming in India: it is time we look beyond the concept of the Big Four species. [PDF]

Trans R Soc Trop Med Hyg
Menon JC, Sreekrishnan TP, Nair SB, Pillay VV, Kanungo S, Aravind MS, Bharti OK, Joseph JK, Pati S.   +8 more
europepmc   +1 more source

Exploring children's experiences of schooling in Tanzania: How the ‘hidden curriculum’ undermines aspirations for sustainable development

Children &Society, EarlyView.
Abstract In the context of aspirations that firmly position education as the key to multiple global development goals, we raise concerns about how education is experienced by many children, particularly in low‐income, postcolonial contexts. Drawing from two, in‐depth qualitative studies in Tanzania, we demonstrate that existing pedagogical practices ...
Laela Adamson, Rhona Brown
wiley   +1 more source

Local Ecological Knowledge and Cultural Perceptions of Snakes in Sudan. [PDF]

Ecol Evol
Baleela RMH, Elamin MEMO, Mohammad A, Saeed SAK.   +3 more
europepmc   +1 more source

Conservation implications of low contemporary connectivity along the Mid‐Atlantic Ridge in hydrothermal vent gastropods

Conservation Biology, EarlyView.
Abstract Polymetallic sulfide deposits produced at hydrothermal vent fields are targets for mining exploitation along the Mid‐Atlantic Ridge, threatening the functioning and resilience of vent ecosystems that provide multiple ecosystem services. Knowledge about connectivity between vents will inform conservation practices.
E. Portanier, A. Tran Lu Y, F. Pradillon, C. Daguin‐Thiébaut, S. Ruault, P. Collins, E. Omnes, S. Fuchs, J. Carlsson, D. Jollivet, M. Matabos   +10 more
wiley   +1 more source