Results 211 to 220 of about 4,985 (284)

Albumin Restores Endothelial Cell Mitochondrial Morphology in Patients With Decompensated Cirrhosis

open access: yesLiver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background & Aims Endothelial cell (EC) activation is a critical driver of disease progression in cirrhosis, contributing to acute decompensation (AD) and acute‐on‐chronic liver failure (ACLF). Although human albumin administration improves EC function in cirrhotic patients with hypoalbuminemia, its direct effects on ECs remain unclear.
Susan E. Fischer   +5 more
wiley   +1 more source

Salvia miltiorrhiza‐Derived Vesicle‐Like Nanoparticles Functionalised Hydrogel With Excellent Ability of Oxidative Stress Modulation and Anti‐Cardiomyocyte Apoptosis for Sepsis‐Induced Myocardial Injury

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3391-3406, May 2026.
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu   +12 more
wiley   +1 more source

Obesity Disrupts H3K4me3‐Mediated Lactate Accumulation and Efferocytosis in Hypoxic Macrophages

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Obesity disrupts macrophage adaptation to hypoxic microenvironments. In lean conditions, hypoxia induces H3K4me3‐dependent transcriptional programs that promote lactate accumulation, histone lactylation, and efficient efferocytosis. Diet‐induced obesity impairs this epigenetic–metabolic response, resulting in reduced lactate accumulation, defective ...
Kentaro Takahashi   +14 more
wiley   +1 more source

Morphological, molecular identification and evaluation of antioxidant activity of seahorses from the Moroccan coasts. [PDF]

open access: yesSaudi J Biol Sci
Salam MR   +6 more
europepmc   +1 more source

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

open access: yesThe FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd   +9 more
wiley   +1 more source

Citizen Science - papers [PDF]

open access: yes, 2016
Goffredo, Stefano
core  

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