Results 61 to 70 of about 42,047 (291)

Optimization of K-Shaped Metal Sealing Ring for Subsea Tubing Hanger Based on Response Surface Method

open access: yesModelling and Simulation in Engineering
The K-shaped metal sealing ring of the subsea tubing hanger is a crucial sealing component ensuring wellhead sealing. Optimizing its structure can enhance the sealing performance of the tubing hanger and improve the reliability of subsea wellhead ...
Huan Xie   +4 more
doaj   +1 more source

Simulation Study on Sealing Performance of Special Threaded Connector Under Vibration Conditions

open access: yesShiyou jixie, 2023
The traditional statics theory cannot effectively explain the sealing failure of special threaded connector caused by pipe string vibration.Therefore,in the paper,based on the theory of energy dissipation,considering the influence of micro contact slip ...
Yu Yang   +5 more
doaj  

Numerical study of turbine rim seals performance with different sealing structures [PDF]

open access: yes, 2022
The unsteady large-scale vortex near the turbine rim has an important influence on the sealing performance. Characteristics and performance of four sealing structures are researched in this paper.
Yang, Qingzhen   +4 more
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Newly structured design and finite element analysis of bionic nonsmooth surface sealing ring of cone bit

open access: yesAdvances in Mechanical Engineering, 2018
The seal is a critical component of a cone bit, whose performance can be reduced because of its large contact area. To reduce stress within the seal, a bionic nonsmooth surface seal was designed and the structural parameters of sealing rings with ...
Yi Zhou, Yinghuan Liu
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin   +8 more
wiley   +1 more source

Effect of Structural Parameters on Performance of Dissolvable Metal Ball Seat Sealing Rings in Frac Plug

open access: yesTechnologies
Aiming at the problems of insufficiently tight sealing of all-metal dissolvable frac plugs and the poor fracturing effect in the extraction of shale gas, the effects of structural parameters on the performance of metal dissolvable ball seat sealing rings
Shunzuo Qiu   +5 more
doaj   +1 more source

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