Results 111 to 120 of about 53,745 (331)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Multi-objective ship’s cargo handling model
Transport, 2015 This paper proposes a new optimization model for ship’s cargo handling operations which solution gives the structure of cargo handling resources required, along with attaining the minimum total ‘in-port’ costs and the minimum of time required for ...
Mirano Hess, Svjetlana Hess
doaj +1 more source
Resource abundance and regional development in China: [PDF]
"Over the past several decades, China has made tremendous progress in market integration and infrastructure development. Demand for natural resources has increased from the booming coastal economies, causing the terms of trade to favor the resource ...
Fan, Shenggen +3 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
npj Materials DegradationCarbon steel and low alloy steel coupons were immersed for 7–8 months in natural marine medium (Les Minimes seaport – Atlantic Ocean, La Rochelle, France) and in laboratory conditions, but using natural seawater sampled in the seaport.
M. Serjaouan +6 more
doaj +1 more source
ANALYSIS OF THE BENEFITS OF INTRA-PORT COMPETITION [PDF]
Intra-port competition is widely regarded as beneficial, for the competitiveness of ports, for local and national economies and for consumers and exporting industries.
Athanasios A. Pallis, Peter W. De Langen
core
, 1995 In a previous article, we explored the problem of finding 14-letter words and names beginning with the letter C and alternating their consonants and vowels regularly: words such as COLONIZABILITY and CAPACITATIVELY.
Borgmann, Dmitri A.
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Lumpy Trade and the Welfare Effects of Administrative Barriers [PDF]
Using detailed U.S. and Spanish export data, we document that administrative trade costs of per shipment nature (documentation, customs clearance and inspection) lead to less frequent and larger-sized shipments, i.e.
Cecília Hornok, Miklós Koren
core
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source