Results 61 to 70 of about 53,745 (331)
Threat Utility of the Seaport Risk Factors: Use of Rough Set-Based Genetic Algorithm
Journal of Marine Science and Engineering, 2022 The threat due to risk factors disrupts supply chain continuity. To ensure supply chain continuity, it is important to understand the interdependency between seaport risk factors and the threat of supply chain disruption, from an economic and risk ...
Muhammad Reza Do Bagus, Shinya Hanaoka
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Maritime Risk in Seaport Operation: A Cross-Country Empirical Analysis with Theoretical Foundations
Asian Journal of Shipping and Logistics, 2018 The maritime industry has witnessed several accidents worldwide. These disasters have raised the awareness of both researchers and policy makers about the importance of risk assessment and safety in marine transportation and seaport operation. This study
Hyuk Soo Cho +2 more
doaj +1 more source
IEEE Access, 2020 In this digital age, ports face stiff competition in global supply chain. Smart ports, as high performing ports, utilize information and communications technology (ICT) to provide a wide range of smart applications, resulting in vastly improved vessels ...
Kok-Lim Alvin Yau +4 more
doaj +1 more source
Implementation Problems of the Rules About the Prevention of Marine Environment Pollution by Sewage and Harmful Substances [PDF]
Lex Portus, 2018 The article deals with the peculiarities of the implementation process of the conventional rules about the prevention of marine environment pollution by sewage from ships and transported harmful substances in the national legislation of Ukraine.
Oleksandr Balobanov, Stefaniia Shmygina
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Risk measures of load loss during service of refrigerated containers in seaports [PDF]
Archives of Transport, 2015 The presented paper is concerned with the problems of assessing the risk level for service chain of refrigerated containers in seaports. This issue has been examined with regard to the losses related to the loss of cargo’s qualitative values.
Ludmiła Filina-Dawidowicz +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source