Results 121 to 130 of about 32,394 (293)

U.S. Customs and Border Protection: Trade Facilitation, Enforcement, and Security [PDF]

open access: yes, 2013
[Excerpt] This report describes and analyzes import policy and CBP’s role in the U.S. import process. (The report does not cover CBP’s role in the U.S. export control system.) The first section of the report describes the three overarching goals of U.S ...
Jones, Vivian C, Rosenblum, Marc R
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Legal status of the sea ports and port policy in Republic of Croatia

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2010
This paper aims at analyzing the legal status of sea ports in the Republic of Croatia, with special overview of the sea ports as maritime domain and at suggesting the objectives of Croatian port policy as well as necessary measures to achieve them ...
Tomislav Batur
doaj  

Role of Seaports and Imported Rats in Seoul Hantavirus Circulation, Africa. [PDF]

open access: yesEmerg Infect Dis, 2023
Castel G   +4 more
europepmc   +1 more source

Globalization and Inequality: Evidence from Within China [PDF]

open access: yes
In this paper, we provide a case study of the impact of globalization on income inequality using data across Chinese regions. The literature on cross-country studies has been criticized because differences in legal systems and other institutions across ...
Shang-Jin Wei, Yi Wu
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

How to Auction an Essential Facility When Underhand Integration Is Possible [PDF]

open access: yes
Regulating seaports is difficult in general, even more so for the weak regulatory institutions common in developing countries. For this reason some countries have awarded these facilities via Demsetz auctions, to the port operator that bids the lowest ...
Alexander Galetovic   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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