Results 171 to 180 of about 32,565 (293)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Emerging Human Fascioliasis in India: Review of Case Reports, Climate Change Impact, and Geo-Historical Correlation Defining Areas and Seasons of High Infection Risk. [PDF]

Trop Med Infect Dis
Mas-Coma S, Cuervo PF, Chetri PB, Tripathi T, Gabrielli AF, Bargues MD.   +5 more
europepmc   +1 more source

Assessment of COVID-19 pandemic effects on ship pollutant emissions in major international seaports. [PDF]

Environ Res, 2021
Liu J, Law AW, Duru O.
europepmc   +1 more source

COMMISSION STAFF WORKING DOCUMENT Accompanying document to the REPORT...ON THE IMPLEMENTATION OF THE TRANS-EUROPEAN TRANSPORT NETWORK GUIDELINES 2004 – 2005 Pursuant to Article 18 of Decision 1692/96/EC {COM(2009) 5 final}. SEC (2009) 18, 20.1.2009 [PDF]

, 2009

core  

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Scoping review of infectious disease prevention, mitigation and management in passenger ships and at ports: mapping the literature to develop comprehensive and effective public health measures. [PDF]

Trop Med Health
Anagnostopoulos L, Vasileiadis S, Kourentis L, Bogogiannidou Z, Voulgaridi I, Nichols G, Kalala F, Speletas M, Hadjichristodoulou C, Mouchtouri VA, EU HEALTHY SAILING project.   +10 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Strengthening Somalia's health system: pathways to achieving International Health Regulations core capacities at points of entry by 2025. [PDF]

Trop Med Health
Hussein SA, Osman MM, Hassan YSA, Hussein AA, Adem R, Ali AN, Yusuf MF, Shurie ANF, Hussein AA, Mohamud OM, Mohamud AM, Ibrahim AM, Ali AA, Umeokonkwo CD.   +13 more
europepmc   +1 more source

Manoeuvring with negative underkeel clearance : 2nd full scale field test in the Port of Delfzijl [PDF]

, 2016
Barth, R, van der Made, CJAW, Vantorre, Marc, Verwilligen, Jeroen   +3 more
core   +1 more source