Results 41 to 50 of about 750,854 (290)

Assessing the Effectiveness and Usability of Personalized Internet Search through a Longitudinal Evaluation [PDF]

open access: yes, 2009
This paper discusses a longitudinal user evaluation of Prospector, a personalized Internet meta-search engine capable of personalized re-ranking of search results. Twenty-one participants used Prospector as their primary search engine for 12 days, agreed
König, Florian   +2 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dynamic Search-Space Pruning Techniques in Path Sensitization [PDF]

open access: yes, 1994
— A powerful combinational path sensitization engine is required for the efficient implementation of tools for test pattern generation, timing analysis, and delay fault testing.
Marques-Silva, Joao, Sakallah, Karem
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Humkinar: Construction of a Large Scale Web Repository and Information System for Low Resource Urdu Language

open access: yesIEEE Access
Online content availability, commercial viability, and technological advancements for English and European languages direct mainstream search engines to prioritize the search results of these high-resource languages.
Muhammad Amir Mehmood, Bilal Tahir
doaj   +1 more source

Smart Search: A Firefox Add-On to Compute a Web Traffic Ranking [PDF]

open access: yes, 2011
Search engines results are typically ordered according to some notion of importance of a web page as well as relevance of the content of a web page to a query. Web page importance is usually calculated based on some graph theoretic properties of the web.
Pamidi, Vijaya
core   +1 more source

Search Engine Optimisation in UK news production [PDF]

open access: yes, 2011
This is an Author's Accepted Manuscript of an article published in Journalism Practice, 5(4), 462 - 477, 2011, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/17512786.2010.551020.This paper represents an exploratory ...
Dick, M
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Multi-keyword multi-click advertisement option contracts for sponsored search

open access: yes, 2015
In sponsored search, advertisement (abbreviated ad) slots are usually sold by a search engine to an advertiser through an auction mechanism in which advertisers bid on keywords.
Chen, Bowei   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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