Results 41 to 50 of about 185,043 (325)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Search Engine Optimization Techniques

open access: yesInternational Journal For Multidisciplinary Research, 2023
The search engine plays a vital role in E-marketing in a modern-day scenario. The search engine provides us the search results. It shows the results as a list. The ultimate goal of a search engine is to optimize the search result. The search engine optimizes the search results based on relevancy.
Rahul Dhiman -, Naveen Bansal -
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Evaluación de la Presencia de los Sitios Web de Turismo de Costa de España en los Motores de Búsqueda

open access: yesARA: Revista de Investigación en Turismo, 2021
The websites of destination marketing organizations are very frequently the first contact between the tourist and the destination.
Lucia Molina Pérez   +2 more
doaj  

Search Engine Optimization (SEO): A Study of important key factors in achieving a better Search Engine Result Page (SERP) Position

open access: yesSukkur IBA Journal of Computing and Mathematical Sciences, 2022
Search Engines (SEs) have become the most significant tool for retrieving information from the World Wide Web (WWW) against user-generated queries.  Presently, the data available on the Internet is growing exponentially in three different dimensions i.e.
Muhammad Iqbal   +4 more
doaj   +1 more source

Multiplicative Bidding in Online Advertising [PDF]

open access: yes, 2014
In this paper, we initiate the study of the multiplicative bidding language adopted by major Internet search companies. In multiplicative bidding, the effective bid on a particular search auction is the product of a base bid and bid adjustments that are ...
Bateni, MohammadHossein   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

SEO strategies in booksellers sector

open access: yesIntangible Capital, 2009
The Internet has consolidated as a new commercial and marketing channel due to the advance of Information and Communication Technologies and the saturation of conventional media channels.
Ferran Sabate   +3 more
doaj   +1 more source

Разработка методики продвижения сайтов социально-образовательной тематики [PDF]

open access: yes, 2014
Sites of socio-educational subjects occupy a considerable part in the cluster of all existing sites. Being popular, these websites need to be promoted, because their quantity is constantly growing.
Андреева, Г. В.   +1 more
core  

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