Results 51 to 60 of about 17,807 (248)

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Integração das técnicas de Search Engine Optimization e User Experience

open access: yesInformação em Pauta
Este estudo analisa o impacto das técnicas de Search Engine Optimization na melhoria da experiência do usuário (User Experience) nos mecanismos de busca.
Gustavo Camossi, Cecilo Merlotti Rodas
doaj   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Result Assessment Tool (RAT): empowering search engine data analysis [PDF]

open access: yesPeerJ Computer Science
The Result Assessment Tool (RAT) is a Python-based software toolkit that enables researchers to analyze results from commercial search engines, social media platforms, and library search systems.
Sebastian Sünkler   +3 more
doaj   +2 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

University ‘Pay-for-grades’: the bait and switch search engine optimization strategies of contract cheating websites in the United States

open access: yesInternational Journal for Educational Integrity
This paper presents the first systematic investigation into the search engine optimization practices of major contract cheating websites in the United States.
Timothy M. Daly, James C. Ryan
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Search engine optimization

open access: yes, 2010
The paper deals with the importance of web page optimization. Internet and its characteristics are shown in the beginning of this paper, as the main source of obtaining information. Web pages should have all the necessary information that people are seeking and should also be ranged as high as possible in the search engines.
openaire   +3 more sources

The Impact of Search Engine Optimization on The Visibility of Research Paper and Citations

open access: yesJOIV: International Journal on Informatics Visualization, 2017
The initial criteria for evaluating a researcher's output is the number of papers published. Furthermore, for the measurement of author's research quality, the number of citations is significant.
Asim Shahzad   +6 more
doaj   +1 more source

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