Results 111 to 120 of about 2,143,335 (271)

Maximization strategies in relationship and career enhances life satisfaction through meaning making among established adults in South Korea

open access: yesBMC Psychology
Background Choosing a partner and job have long been regarded as important developmental milestones to reach in adulthood. In a collective cultural context with high familial and societal expectations to commit to a relationship and job by age 30 ...
Yerin Shim, Yun-Jeong Shin, Ji-yeon Lee
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Becoming a guide for pilgrims in a time of secularization

open access: yesChurch, Communication and Culture, 2018
The goal of this case study is threefold: first, to introduce the concept of postmodern pilgrim, leveraging on two pilgrimage experiences in Switzerland; second, to propose a model (PEARL) for developing training modules for pilgrim guides; and finally ...
Terry Inglese
doaj   +1 more source

Content or context? Searching for musical meaning in task-based interactive information retrieval [PDF]

open access: yes, 2008
Creative professionals search for digital music to accompany moving images using interactive information retrieval systems run by music publishers and record companies.
Inskip, C., MacFarlane, A., Rafferty, P.
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Man’s Search For Meaning by Viktor E. Frankl [PDF]

open access: yes, 2015
Recensão crítica à obra de Viktor E. Frankl “Man’s Search For Meaning”, 2015“Man’s Search For Meaning” is one the best book I have read about searching for meaning in life.
Sousa, Ivo Dias de
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Finding the Original Meaning of American Criminal Procedure Rights: Lessons from Reasonable Doubt’s Development [PDF]

open access: yes, 2012
[Excerpt] “The prosecution must prove every element of the crime beyond a reasonable doubt for a valid conviction. The Constitution nowhere explicitly contains this requirement, but the Supreme Court in In re Winship1 stated that due process commands it.
Jonakait, Randolph N.
core   +2 more sources

Dark Atoms of Dark Matter and their Stable Charged Constituents

open access: yes, 2011
Direct searches for dark matter lead to serious problems for simple models with stable neutral Weakly Interacting Massive Particles (WIMPs) as candidates for dark matter. A possibility is discussed that new stable quarks and charged leptons exist and are
Khlopov, Maxim Yu.
core   +1 more source

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