Results 121 to 130 of about 17,504,389 (343)

Ordered search in differentiated markets [PDF]

open access: yes, 2009
This note presents an ordered search model in which consumers search both for price and product fitness. We construct an equilibrium in which there is price dispersion and prices rise in the order of search.
Zhou, J., Zhou, Jidong
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

From the Theory of Globalization to the Theory of Cultural Globalization: The Theoretical Search of Chinese Philosophers

open access: yesКонцепт: философия, религия, культура
The article is devoted to the analysis of Chinese philosophers’ scientific positions on globalization and cultural globalization. With the ongoing debate on globalization, its current state and long-term consequences, it is of relevance to consider the ...
Hong Zhao
doaj   +1 more source

Labour Supply, Search and Taxes [PDF]

open access: yes
Classical labour supply theory is one of the most sophisticated parts of labour economics. Yet, there is no compelling theoretical reason to believe in an outcome on a classical labour supply curve and it is unclear whether it is a good empirical ...
Alan Manning
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Geopolics in Development of Civilizational Theory: in Search for Peace

open access: yesRUDN Journal of Political Science, 2010
In the article the author explores the manifestation of geopolitics in the civilizational theories, how this part of political science has an impact on the interaction of peoples and nations in terms of civilizations' development.
B U Kitinov
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Key Elasticities in Job Search Theory: International Evidence [PDF]

open access: yes
This paper exploits the informational value of search theory, after Lancaster and Chesher (1983), in conjunction with survey data on the unemployed to calculate key reservation wage and duration elasticities for most EU-15 nations.
Mário Centeno   +2 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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