Results 161 to 170 of about 808,219 (241)

A rare case report of vascular Ehlers-Danlos syndrome as a pulsatile neck mass with an internal carotid artery aneurysm. [PDF]

Radiol Case Rep
Rahman MF, Azad J, Biswas N, Jahan F, Shimu FS, Hussen MD, Zeehad MMR.   +6 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Exploring educational approaches and strategies for developing evidence synthesis skills among pharmacy students: a scoping review protocol. [PDF]

BMJ Open
Haritha K, Shetty VS, Rajendran R, Sekhar M S, Kunhikatta V, Unnikrishnan B, Khan S, Gunning TK, Athan E, Saha SK, Thunga G.   +10 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Context-dependent influence of path integration on nest plume following in desert ants. [PDF]

iScience
Spehr R, Eschenhagen J, Knaden M.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Mapping digital literacies interventions in health professions education and exploring the implications for trainees' online advocacy and knowledge mobilisation activities: a critical scoping review protocol. [PDF]

BMJ Open
Giroux CM, Thomas A, Sikora L, LaDonna K.   +3 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Searching ESTs

BioTechniques, 1998
Stuart M. Brown
doaj   +1 more source

The Efficacy of Adjunctive Platelet Concentrates in Combined Guided Tissue Regeneration and Bovine Bone Grafting for Intrabony Defects: A Systematic Review. [PDF]

Clin Exp Dent Res
Chan R, Lau H, Liao M, Park J, Ting A, Xu YY, Fernandez-Medina T.   +6 more
europepmc   +1 more source