Results 31 to 40 of about 462,816 (265)

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot   +6 more
wiley   +1 more source

Occurrences and frequency of fungi and detection of mycotoxins on poultry rations in Yemen

open access: yesBulletin of the National Research Centre, 2018
Background Fungi were grown elsewhere in the soil, water, and food, and fungi cause many of the problems during growth on food in stores. This study investigated the occurrence and frequency of fungi in four governorates in Yemen.
Hamid Moh Algabr   +4 more
doaj   +1 more source

Mutual search

open access: yesJournal of the ACM, 1999
We introduce a search problem called “mutual search” where k agents, arbitrarily distributed over n sites, are required to locate one another by posing queries of the form “Anybody at site i ?”.
H.M. Buhrman (Harry)   +5 more
openaire   +4 more sources

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte   +5 more
wiley   +1 more source

Role of biological rhythms in the performance of physical activity

open access: yesJournal of Physical Fitness and Sports Medicine, 2017
Most organisms display various periodicities. Periodicity has been observed in humans in association with sleep, body temperature and hormone secretion. The molecular mechanisms involved are being elucidated by the investigation of clock genes in mammals.
Takahiro Sato   +2 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko   +19 more
wiley   +1 more source

Partitioning Search Spaces of a Randomized Search [PDF]

open access: yesFundamenta Informaticae, 2009
This paper studies the following question: given an instance of the propositional satisfiability problem, a randomized satisfiability solver, and a cluster of n computers, what is the best way to use the computers to solve the instance? Two approaches, simple distribution and search space partitioning as well as their combinations are investigated both
Niemelä Ilkka   +2 more
openaire   +3 more sources

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