Results 91 to 100 of about 185,887 (355)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Managing Contributions to the Unified Astronomy Thesaurus

EPJ Web of Conferences, 2018
The Unified Astronomy Thesaurus (UAT) project managers have long defined the UAT as "an open, interoperable, and community-supported thesaurus." How do we solicit the detailed, comprehensive, and consistent community feedback that is required to keep the
Frey Katie, Weissman Sarah, Kern Barbara, Lagerstrom Jill, Peek Josh, Accomazzi Alberto   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

CD34-positive cells and their subpopulations characterized by flow cytometry analyses on the bone marrow of healthy allogenic donors

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Counting and separating hematopoietic stem cells from different sources has importance for research and clinical assays. Our aims here were to characterize and quantify hematopoietic cell populations in marrow donors and to ...
Jerusa Martins Carvalho, Marlon Knabben de Souza, Valéria Buccheri, Cláudia Viviane Rubens, José Kerbauy, José Salvador Rodrigues de Oliveira   +5 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Using the Complete Sequences for Sorting Natural Numbers

Известия Иркутского государственного университета: Серия "Математика", 2017
Complete sequences are defined as infinite sequences of natural numbers, with the help of which it is possible to represent any other natural number.
Y. N. Artamonov
doaj   +1 more source

Dating Preferences and Meeting Opportunities in Mate Choice Decisions [PDF]

Much empirical evidence shows that female and male partners look alike along a variety of attributes. It is however unclear how this positive sorting comes about, because marriage is an equilibrium outcome arising from a process that entails searching ...
Marco Francesconi, Mich�le Belot
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Corrigendum: Searching for Small Molecules with an Atomic Sort [PDF]

, 2020
Brendan M. Duggan, Reiko Cullum, William Fenical, Luis A. Amador, Abimael D. Rodrı́guez, James J. La Clair   +5 more
openalex   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source