Background. Natural medicinal products are commonly used as a remedy against malaria infections in African populations and have become a major source of information for the screening of new and more effective antiplasmodial molecules. Therefore, in vitro studies are needed to validate the efficacy of these medicinal products and to explore the ...
Hamirath O. Lagnika +10 more
wiley +1 more source
Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study. [PDF]
BACKGROUND: The I164L mutation on the dhfr gene confers high level resistance to sulfadoxine-pyrimethamine (SP) but it is rare in Africa except in a cluster of reports where prevalence >10% in highland areas of southwest Uganda and eastern Rwanda.
Abeku, Tarekegn A +8 more
core +1 more source
Co-morbidity of malnutrition with falciparum malaria parasitaemia among children under the aged 6–59 months in Somalia: a geostatistical analysis [PDF]
Background Malnutrition and malaria are both significant causes of morbidity and mortality in African children. However, the extent of their spatial comorbidity remains unexplored and an understanding of their spatial correlation structure would inform ...
Berkley, James +7 more
core +3 more sources
A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [PDF]
Richard Kajubi +12 more
openalex +1 more source
Receipt of seasonal malaria chemoprevention by age-ineligible children and associated factors in nine implementation states in Nigeria [PDF]
Taiwo Ibinaiye +8 more
openalex +1 more source
Seasonal Malaria chemoprevention (SMC) is one of the large-scale life-saving malaria interventions initially recommended for the Sahel subregion, including Burkina Faso and recently extended to other parts of Africa.
Paul Sondo +13 more
doaj
Review of mass drug administration for malaria and its operational challenges. [PDF]
Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance.
Chen, Ingrid +12 more
core +1 more source
Reactive community-based self-administered treatment against residual malaria transmission: study protocol for a randomized controlled trial [PDF]
Background: Systematic treatment of all individuals living in the same compound of a clinical malaria case may clear asymptomatic infections and possibly reduce malaria transmission, where this is focal.
A Kaneko +42 more
core +3 more sources
Age‑shifting in malaria incidence as a result of induced immunological deficit: a simulation study [PDF]
Effective population-level interventions against Plasmodium falciparum malaria lead to age-shifts, delayed morbidity or rebounds in morbidity and mortality whenever they are deployed in ways that do not permanently interrupt transmission.
Hodel, Eva Maria
core +1 more source
The Malaria Policy Advisory Committee to the World Health Organization met for the first time from 31 January to 2 February 2012 in Geneva, Switzerland. This article provides a summary of the discussions, conclusions and recommendations from that meeting,
doaj +1 more source

