Role of phytochemicals in the chemoprevention of tumors [PDF]
Phytochemicals are plant-derived secondary metabolites, which may exert many biological activities in humans, including anticancer properties. Although recent findings appear to support their role in cancer prevention and treatment, this issue is still controversial.
arxiv
Addressing implementation uncertainty in postdischarge malaria chemoprevention : Determinants of adherence, cost-effectiveness, and the value of further research in Malawi and other malaria-endemic African countries [PDF]
Postponed access: the file will be accessible after 2025-11-08Bakgrunn: Malaria fortsetter å være en ledende årsak til dødsfall og dødelighet for barn som bor i malaria-endemiske områder i Afrika sør for Sahara.
Kühl, Melf-Jakob
core +1 more source
Avoiding another lost decade in reducing malaria burden in African infants and young children [PDF]
Alonso, Pedro L+5 more
core +3 more sources
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01 E [PDF]
The recently deployed RTS,S/AS01E malaria vaccine induces a strong antibody response to the circumsporozoite protein (CSP) on the surface of the Plasmodium falciparum sporozoite which is associated with protection.
Ali, M. Sanni+23 more
core +2 more sources
Malaria is preventable, but the burden of disease remains high with over 249 million cases and 608,000 deaths reported in 2022. Historically, the most important protective interventions have been vector control and chemopreventive medicines with over 50 ...
Myriam El Gaaloul+12 more
doaj +1 more source
Robust evaluation of vaccine effects based on estimation of vaccine efficacy curve [PDF]
Background: The Cox model and its extensions assuming proportional hazards is widely used to estimate vaccine efficacy (VE). In the typical situation that VE wanes over time, the VE estimates are not only sensitive to study duration and timing of vaccine delivery in relation to disease seasonality but also biased in the presence of sample attrition ...
arxiv
Monthly malaria chemoprevention shows potential in an area of very high, perennial malaria transmission [PDF]
Cairns, M, Walker, PG
core +2 more sources
Nigeria suffers the world's greatest malaria burden, with approximately 51 million cases and 207,000 deaths reported annually, SMC has been widely used in the Sahel since the World Health Organization recommended it in 2012 for children under the age of ...
Muslim Adamu , Abdullahi Sabo Muhammad Yahaya Saleh
doaj
Large-scale delivery of seasonal malaria chemoprevention to children under 10 in Senegal: an economic analysis. [PDF]
Seasonal Malaria Chemoprevention (SMC) is recommended for children under 5 in the Sahel and sub-Sahel. The burden in older children may justify extending the age range, as has been done effectively in Senegal.
Cissé, Badara+9 more
core +1 more source