Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Integrated Whole-Exome and Transcriptome Sequencing Indicated Dysregulation of Cholesterol Metabolism in Eyelid Sebaceous Gland Carcinoma. [PDF]
Transl Vis Sci Technol, 2023 Wang Y +6 more
europepmc +1 more source
Steatocystoma multiplex: those little tumours. [PDF]
, 2014 de Moll, Ellen H. +2 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian +7 more
wiley +1 more source
The Sebaceous Gland: A Key Player in the Balance Between Homeostasis and Inflammatory Skin Diseases. [PDF]
CellsMosca S +4 more
europepmc +1 more source
Advanced Science, EarlyView.In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang +8 more
wiley +1 more source
Lipid Dysregulation in Sebaceous Gland Disorders and the Impact of Sphingolipid Metabolism on Acne Pathogenesis. [PDF]
CureusMiner K +8 more
europepmc +1 more source
The World's First Acne Dysbiosis-like Model of Human 3D Ex Vivo Sebaceous Gland Colonized with <i>Cutibacterium acnes</i> and <i>Staphylococcus epidermidis</i>. [PDF]
Microorganisms, 2023 Forraz N +8 more
europepmc +1 more source
Aryl Sulfatase in the Sebaceous Glands of Mouse Skin A Combined Electron Microscope and Cytochemical Study**From the Department of Biology, Royal Free Hospital School of Medicine, 8, Hunter Street, London, W.C.1. [PDF]
, 1968 Cruz Villalón, Jesús +2 more
core +1 more source
Advanced Science, EarlyView.An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang +7 more
wiley +1 more source