Results 211 to 220 of about 29,112 (287)

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Clinicopathologic Features of Eyelid Sebaceous Gland Carcinoma Requiring Immunohistochemical Diagnosis. [PDF]

Ocul Oncol Pathol
Yunoki T, Miyakoshi A, Hayashi A.
europepmc   +1 more source

Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids [PDF]

, 2015
Ching-Hsi Hsiao, Ching-Yi Cheng, David Hui-Kang Ma, Hsuan-Ying Huang, Lung-Kun Yeh, Nan-Kai Wang, Shu-Ya Wu, Yueh-Ju Tsai   +7 more
core   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira, David Agorku, Andre Rosa, Julia Roosz, Lena Christ, Nicole Anderle, Ajinkya Kulkarni, Abir Hussein, Sana S. Sayedipour, Omar F. Luna, Tobias Legler, Philipp Ströbel, Fernando Albericio, Luis Cruz, Phillipp Beckhove, Peter Loskill, Frauke Alves, M. Andrea Markus, Fernanda Ramos‐Gomes   +18 more
wiley   +1 more source

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Eyelid sebaceous gland carcinoma: a protocol for a systematic review and meta-analysis of clinicopathological studies of prevalence. [PDF]

BMJ Open
Thagaard MS, Vest SD, Heegaard S, Marcussen N.   +3 more
europepmc   +1 more source

Sebaceous Gland Carcinoma of Lid: Masquerading as a Recurring Chalazion.

Int J Appl Basic Med Res, 2021
Sahu SK, Sen S, Poddar C.
europepmc   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

Neoadjuvant Chemotherapy in Non-Metastatic Eyelid Sebaceous Gland Carcinoma: A Report in 10 Cases. [PDF]

Ocul Oncol Pathol
Kumar N, Meel R, Bakhshi S, Pushpam D, Pushker N, Bajaj MS, Kashyap S, Sen S, Pathy S, Sharma S.   +9 more
europepmc   +1 more source

Management of recurrent sebaceous gland carcinoma. [PDF]

Eye (Lond), 2020
McGrath LA, Currie ZI, Mudhar HS, Tan JHY, Salvi SM.   +4 more
europepmc   +1 more source