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Development of a non-invasive diagnostic method for pathogenic RNA viruses using sebum wiped from the cat’s body surface [PDF]

open access: yesScientific Reports
The development of non-invasive diagnostic methods for zoonotic viral infections is important for animal welfare and public health. Sebum-based diagnostic methods using commercial oil-blotting films have been used for SARS-CoV-2 detection in humans, but ...
Yuri V Fukushima   +3 more
doaj   +2 more sources

Age-related evaluation of skin barrier parameters in retrievers [PDF]

open access: yesFrontiers in Veterinary Science
IntroductionA disruption in the skin barrier, which serves as the primary defense against external pathogens, can lead to skin disorders. In humans, various factors influence the skin barrier, including age and anatomical site.
Eun-Hae Lee   +6 more
doaj   +2 more sources

A review of sebum in mammals in relation to skin diseases, skin function, and the skin microbiome [PDF]

open access: yesPeerJ, 2023
Diseases vary among and within species but the causes of this variation can be unclear. Immune responses are an important driver of disease variation, but mechanisms on how the body resists pathogen establishment before activation of immune responses are
Karen Vanderwolf   +2 more
doaj   +2 more sources

A Real-Time Detection Device for the Rapid Quantification of Skin Casual Sebum Using the Oil Red O Staining Method

open access: yesSensors, 2022
The human skin sebum suggests that it (along with other epidermal surface lipids) plays a role in skin barrier formation, the moderation of cutaneous inflammation, and antimicrobial defense.
Kung Ahn   +8 more
doaj   +1 more source

Application of Sebum Lipidomics to Biomarkers Discovery in Neurodegenerative Diseases

open access: yesMetabolites, 2021
Lipidomics is strategic in the discovery of biomarkers of neurodegenerative diseases (NDDs). The skin surface lipidome bears the potential to provide biomarker candidates in the detection of pathological processes occurring in distal organs.
Stefania Briganti   +7 more
doaj   +1 more source

Sweat and Sebum Preferences of the Human Skin Microbiota

open access: yesMicrobiology Spectrum, 2023
The microorganisms inhabiting human skin must overcome numerous challenges that typically impede microbial growth, including low pH, osmotic pressure, and low nutrient availability.
Mary Hannah Swaney   +3 more
doaj   +1 more source

Fatty Acid Profiling in Facial Sebum and Erythrocytes From Adult Patients With Moderate Acne

open access: yesFrontiers in Physiology, 2022
Fatty acid (FA) metabolism has been involved in acne vulgaris, a common inflammatory skin disease frequently observed in adolescents and adults, but it remains poorly defined whether the distributions or location of FA in facial sebum and those in the ...
Ke Cao   +6 more
doaj   +1 more source

Epidermal Growth Factor Modulates Palmitic Acid-Induced Inflammatory and Lipid Signaling Pathways in SZ95 Sebocytes

open access: yesFrontiers in Immunology, 2021
Epidermal growth factor (EGF) acts as a paracrine and autocrine mediator of cell proliferation and differentiation in various types of epithelial cells, such as sebocytes, which produce the lipid-rich sebum to moisturize the skin.
Dániel Törőcsik   +9 more
doaj   +1 more source

The Influence of Increasing Concentrations of AMPD on the Efficacy of Its Penetration into a Model Skin Sebum Layer

open access: yesPharmaceutics, 2020
Alcoholamines are widely used as auxiliary substances in various topical preparations. Their impact on the components of skin sebum allows them to be used in preparations that cleanse the skin of sebum in hair follicles.
Agnieszka Kostrzębska, Witold Musiał
doaj   +1 more source

Efficacy of FRO on Acne Vulgaris Pathogenesis

open access: yesPharmaceutics, 2023
Acne vulgaris is a common skin disease characterized by increased sebum production, inflammation, and Cutibacterium acnes (CA: formerly Propionibacterium acnes) hyperproliferation in pilosebaceous follicles.
Jung-Eun Kim   +4 more
doaj   +1 more source

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