Results 51 to 60 of about 13,270 (282)
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
Advanced Science, EarlyView.A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
Microorganisms, 2021 The skin microbiome and sebum may be associated with inflammation-related diseases of the scalp. To assess the pathogenesis and progression of androgenetic alopecia (AGA), we analyzed the composition of sebum and the bacterial and fungal microbiomes of ...
Kazuhiro Suzuki +6 more
doaj +1 more source
Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management
Advanced Science, EarlyView.A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao +9 more
wiley +1 more source
The production and composition of rat sebum is unaffected by 3 Gy gamma radiation
, 2010 The aim of this work was to use metabolomics to evaluate sebum as a source of biomarkers for gamma-radiation exposure in the rat, and potentially in man.
Monika Ledermann +7 more
core +1 more source
Mechanisms of lipid extraction from skin lipid bilayers by sebum triglycerides [PDF]
, 2018 The skin surface, our first barrier against the external environment, is covered by the sebum oil, a lipid film composed of sebaceous and epidermal lipids, which is important in the regulation of the hydration level of our skin.
Noro, Massimo G +4 more
core +1 more source
Advanced Science, EarlyView.Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li +9 more
wiley +1 more source
The Needle‐Free Frontier: Redefining the Limits of Transdermal Insulin Delivery
Exploration, EarlyView.Wei and colleagues reported a pH‐responsive, charge‐switchable polyzwitterionic polymer carrier that achieves non‐invasive transdermal insulin delivery without external energy input. The approach leverages adaptive compatibility with the cutaneous microenvironment to shuttle functional macromolecules across intact skin and achieve definitive systemic ...
Junge Chen +4 more
wiley +1 more source
Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease
Nature Communications, 2021 Studies of metabolites in neurodegeneration have not yet used sebum as a source fluid. Here the authors demonstrate the potential of metabolomics of sebum samples from individuals with Parkinson’s disease and controls.
Eleanor Sinclair +10 more
doaj +1 more source
Correlation Between Sebum Level and Follicular Fluorescence in Acne Vulgaris Patients
, 2022 important factors, including follicular epidermal hyperproliferation, increased sebum production, increased activity of C. acnes and inflammation. Increased sebum levels can increase the production of porphyrins which appear as redorange fluorescence ...
Donytasari, Fitri Meutia
core +1 more source
Lipidomics of facial sebum in the comparison between acne and non-acne adolescents with dark skin
Scientific Reports, 2021 Lipidomics is advantageous in the study of sebum perturbations occurring in acne. An extended evaluation of the sebum lipid profiles in acne-prone sebaceous areas is lacking in dark skin.
Obumneme Emeka Okoro +5 more
doaj +1 more source