Results 171 to 180 of about 17,674,138 (204)

Comparative Analysis of Poly(Ethylene Glycol) (PEG) and Poly(2‐Ethyl‐2‐Oxazoline) (PEtOx) for Organic Solvent‐Free Lipid Nanoparticle Formulations

open access: yesAngewandte Chemie International Edition, EarlyView.
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber   +21 more
wiley   +1 more source

Phenonium‐Ion‐Mediated Skeletal Editing of Paracyclophanes

open access: yesAngewandte Chemie International Edition, EarlyView.
Phenonium‐ion chemistry enables the modular skeletal editing of paracyclophanes. Regioselective nucleophilic trapping expands one or both aliphatic bridges, enables iterative access to higher paracyclophane homologues, and translates bridge topology into a functional design parameter, as demonstrated with a bridge‐expanded TADF emitter.
Tilman Köhler   +7 more
wiley   +1 more source

Adiabatic Pulse Shape Influence on the Orientation Dependence of T<sub>1ρ</sub> Relaxation. [PDF]

open access: yesMagn Reson Med
L de Moura H   +4 more
europepmc   +1 more source

Distinct Molecular Pathways Supporting Sjögren Disease Clusters and Disease Progression

open access: yesArthritis &Rheumatology, EarlyView.
Objective Sjögren disease (SjD) is a heterogeneous autoimmune disease. We aimed to investigate blood transcriptomic signatures and disease progression among three recently defined clusters of patients with SjD: (1) B cell active disease with low symptom burden (BALS), (2) high systemic activity (HSA), and (3) low systemic activity with high symptom ...
Sacha E. Silva‐Saffar   +6 more
wiley   +1 more source

Progressive damage mechanism of rock-anchoring interface under cyclic impact loading. [PDF]

open access: yesSci Rep
Wang P   +8 more
europepmc   +1 more source

Dataset for studying deformation in 3D patient-specific pulmonary artery anatomies. [PDF]

open access: yesSci Data
Pérez-Cualtán CE   +8 more
europepmc   +1 more source

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