Diverging Liquid–Liquid Phase Separation Behavior of Different Recombinant Major Ampullate Spidroins
Fibers spun from the MaSp1‐derivative as well as MaSp1‐MaSp2‐mixtures provide a deeper insight into the assembly process of the spidroins and how hierarchical architectures of spider silk fibers could be achieved. ABSTRACT Spider silk fibers show exceptional mechanical properties, based on their underlying spider silk proteins (spidroins) as well as a ...
Tim Schiller +2 more
wiley +1 more source
A Symmetry-Based Perspective Correction Method for High-Speed Deformation Analysis of Circular Blast-Loaded Plates. [PDF]
Shehu E +5 more
europepmc +1 more source
α‐Synuclein Forms Distinct Micelle‐Like Assemblies at Low Ionic Strengths
At high ionic strength, α‐synuclein forms diverse assemblies, including oligomers, fibrils, and condensates. Here, we show that at low ionic strength, α‐synuclein adopts a distinct, low‐abundance assembly state. These assemblies maintain a constant size above a critical concentration and do not coalesce, suggesting a micelle‐like organization ...
Sophie Hertel +10 more
wiley +1 more source
Hydrogen Solubility in Metal Membranes: Critical Review and Re-Elaboration of Literature Data. [PDF]
Prenesti G +5 more
europepmc +1 more source
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho +13 more
wiley +1 more source
Algebraic evaluation of optimization in tumors classification with numerical assessments via a flask-react web interface. [PDF]
Houssa N, Abdelalim S, Elmouki I.
europepmc +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
Altering MRI rotating frame relaxations by changing the truncation level of Hyperbolic Secant pulse. [PDF]
Ponticorvo S +7 more
europepmc +1 more source
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang +14 more
wiley +1 more source
Numerical simulation of mechanical properties of a new type of assembly shear wall horizontal connection device. [PDF]
Tian P +5 more
europepmc +1 more source

