Results 41 to 50 of about 10,995,154 (282)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Mathematics, 2022 The Jiles-Atherton model was widely used in the description of the system with hysteresis, and the solution for the model was important for real-time and high-precision control.
Guangming Xue +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
, 2011 Cubic polynomial, Newton's MethodSteps of the secant root finding method for a cubic polynomial. The secant method for numerical root finding of the functions f consists of the steps xk+1= xk – f(xk)(xk-xk-1)/(f(xk)
Trott, Michael
core +2 more sources
The Convergence Ball and Error Analysis of the Relaxed Secant Method
Advances in Mathematical Physics, 2017 A relaxed secant method is proposed. Radius estimate of the convergence ball of the relaxed secant method is attained for the nonlinear equation systems with Lipschitz continuous divided differences of first order.
Rongfei Lin +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2016 Cubic polynomial, Newton's MethodSteps of the secant root finding method for a cubic polynomial. The secant method for numerical root finding of the functions f consists of the steps xk+1= xk – f(xk)(xk-xk-1)/(f(xk)
Trott, Michael
core +2 more sources
Modelling and solvability of a class steady-state metal-forming problems
Nonlinear Engineering, 2014 For a class of steady-state metal-forming problems, with rigid-plastic, incompressible, strain-rate dependent material model and with unilateral contact and nonlocal Coulomb’s frictional boundary conditions, a variational inequality formulation ...
Angelov T. A.
doaj +1 more source