Decoding kratom: molecular mechanisms and epigenetic factors in use and dependence. [PDF]
Misnan E +4 more
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Genomic features and the transcriptional regulation of secondary metabolite biosynthesis of endophytic fungus <i>Xylaria</i> sp. VDL4 isolated from <i>Vaccinium dunalianum</i>. [PDF]
Li L +12 more
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The Structure of Carboxyl Methyltransferase Provides Insights Into the Substrate Specificity and Divergent Evolution of Iridoid. [PDF]
Li L +7 more
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Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. [PDF]
Hwang J +21 more
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Microbial elicitors to metabolic reprogramming: an integrative model of plant-microbe interactions. [PDF]
Hembram DB +4 more
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Biosynthetic Origin of the Methoxy Group in Quinine and Related Cinchona Alkaloids
Lombe BK +4 more
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Abstract The novel structure of hunterioside, the first example of monoterpenoid indole alkaloids carrying a disaccharide, was confirmed by chemical synthesis starting from tryptamine, secologanin, and a newly-developed gulucosyl donor, which selectively gives α-gluco type glycosidic linkage in the reaction with a secologanin derivative.
Hiromitsu Takayama, Norio Aimi
exaly +2 more sources
A cell suspension culture of Tabernaemontana elegans lost its ability to produce alkaloids after a prolonged period of subculture. To determine whether it was still capable of performing the later steps of the alkaloid biosynthetic pathway, the culture was fed with tryptamine and loganin.
Rob Verpoorte, R van der Heijden
exaly +2 more sources
A transgenic Saccharomyces cerevisiae was constructed containing the cDNAs coding for strictosidine synthase (STR) and strictosidine beta-glucosidase (SGD) from the medicinal plant Catharanthus roseus. Both enzymes are involved in the biosynthesis of terpenoid indole alkaloids. The yeast culture was found to express high levels of both enzymes.
Rob Verpoorte +2 more
exaly +3 more sources
An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine [PDF]
The secoiridoid glucoside secologanin is the terpenoid building block in the biosynthesis of terpenoid indole alkaloids. A method for its determination in plant tissues and cell suspension cultures has been developed.
Rob Verpoorte +2 more
exaly +1 more source

