Results 81 to 90 of about 73,340 (107)

Decoding kratom: molecular mechanisms and epigenetic factors in use and dependence. [PDF]

open access: yesTransl Psychiatry
Misnan E   +4 more
europepmc   +1 more source

Ancient gene clusters govern the initiation of monoterpenoid indole alkaloid biosynthesis and C3 stereochemistry inversion. [PDF]

open access: yesNat Commun
Hwang J   +21 more
europepmc   +1 more source
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First synthesis of hunterioside, a novel disaccharide carrying monoterpenoid indole alkaloid, by assembly of three components, tryptamine, secologanin, and a newly-developed glucosyl donor

Tetrahedron Letters, 1999
Abstract The novel structure of hunterioside, the first example of monoterpenoid indole alkaloids carrying a disaccharide, was confirmed by chemical synthesis starting from tryptamine, secologanin, and a newly-developed gulucosyl donor, which selectively gives α-gluco type glycosidic linkage in the reaction with a secologanin derivative.
Hiromitsu Takayama, Norio Aimi
exaly   +2 more sources

Alkaloid formation in cell suspension cultures of Tabernaemontana elegans after feeding of tryptamine and loganin or secologanin

Plant Cell, Tissue and Organ Culture, 2002
A cell suspension culture of Tabernaemontana elegans lost its ability to produce alkaloids after a prolonged period of subculture. To determine whether it was still capable of performing the later steps of the alkaloid biosynthetic pathway, the culture was fed with tryptamine and loganin.
Rob Verpoorte, R van der Heijden
exaly   +2 more sources

Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast

Applied Microbiology and Biotechnology, 2001
A transgenic Saccharomyces cerevisiae was constructed containing the cDNAs coding for strictosidine synthase (STR) and strictosidine beta-glucosidase (SGD) from the medicinal plant Catharanthus roseus. Both enzymes are involved in the biosynthesis of terpenoid indole alkaloids. The yeast culture was found to express high levels of both enzymes.
Rob Verpoorte   +2 more
exaly   +3 more sources

An assay for secologanin in plant tissues based on enzymatic conversion into strictosidine [PDF]

open access: yesPhytochemical Analysis, 1998
The secoiridoid glucoside secologanin is the terpenoid building block in the biosynthesis of terpenoid indole alkaloids. A method for its determination in plant tissues and cell suspension cultures has been developed.
Rob Verpoorte   +2 more
exaly   +1 more source

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