Results 241 to 250 of about 38,837 (270)

A Clinical Medication Review Focused on Deprescribing in Older Patients With Hyperpolypharmacy: A Mixed‐Methods Feasibility Study

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
ABSTRACT To address challenges in deprescribing, we investigated the feasibility of an intervention consisting of a clinical medication review (CMR) focused on deprescribing, supported by a training programme for healthcare providers (HCPs) among older patients with hyperpolypharmacy (≥ 10 chronic medications) in primary care.
Gert Baas, Mette Heringa, Sanne Verdoorn, Henk‐Frans Kwint, Eman Badawy, Jacobijn Gussekloo, Marcel Bouvy   +6 more
wiley   +1 more source

A Multicentre, 4‐Year Mirror‐Image Study Comparing the Effectiveness of Long‐Acting Injectable Antipsychotics in the Treatment of Bipolar Disorder: Results From the LAICO Study

Bipolar Disorders, Volume 28, Issue 1, February 2026.
ABSTRACT Background This was a 4‐year mirror‐image study of adult patients diagnosed with bipolar disorder (BD) assessing the effects on treatment continuation and hospitalisation between aripiprazole 1‐month (A1M), risperidone‐LAI (R‐LAI) and the monthly and 3‐monthly formulations of paliperidone palmitate (PP1M, PP3M).
Juan Antonio García‐Carmona, Joshua Barnett, María Pilar Campos‐Navarro, Katie Mason, Jorge Simal‐Aguado, Sofia Pappa   +5 more
wiley   +1 more source

Second-Generation Antipsychotics Induce Metabolic Disruption in Adipose Tissue-Derived Mesenchymal Stem Cells Through an aPKC-Dependent Pathway. [PDF]

Cells
Varalda M, Venetucci J, Nikaj H, Kankara CR, Garro G, Keivan N, Bettio V, Marzullo P, Antona A, Valente G, Gentilli S, Capello D.   +11 more
europepmc   +1 more source

Long-Term Effects of Early Adolescent Second-Generation Antipsychotic Exposure on Body Weight, Caloric Intake, and Metabolism-Associated Gene Expression [PDF]

Paul L. Soto, Michael E. Young, Serena Nguyen, Megan Federoff, Mia M Goodson, Christopher D. Morrison, Heidi M. Batdorf, Susan J. Burke, J. Jason Collier   +8 more
openalex   +1 more source

Advancing the measurement of psychotherapy outcomes for youth with irritability using in vivo ecological momentary assessment: an exploratory observational study

Child and Adolescent Mental Health, Volume 31, Issue 1, Page 33-40, February 2026.
Background Ecological momentary assessment (EMA) can reveal naturalistic within‐person changes in symptoms and behaviors, essential for examining psychotherapy's effectiveness. However, no prior study has leveraged EMA to assess real‐time, naturalistic changes of clinical symptoms during psychotherapy in youth with clinically impairing irritability ...
Reut Naim, Urmi Pandya, Shannon Shaughnessy, Ramaris E. German, Lauren M. Henry, Katharina Kircanski, Melissa A. Brotman   +6 more
wiley   +1 more source

Impact of second-generation antipsychotics monotherapy or combined therapy in cytokine, lymphocyte subtype, and thyroid antibodies for schizophrenia: a retrospective study. [PDF]

BMC Psychiatry
Guo X, Kong L, Wen Y, Chen L, Hu S.
europepmc   +1 more source

Time-to-First Discontinuation, Adherence and Persistence in New Users of Second-Generation Antipsychotics

, 2016
Henry C. Ndukwe, Prasad S. Nishtala
openalex   +2 more sources

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source