Results 131 to 140 of about 122,957 (282)

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

open access: yesBMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen   +9 more
wiley   +1 more source

The Contingent Eco‐Innovation–Firm Performance Link: A Global Systematic Literature Review and Future Research Agenda

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The relationship between eco‐innovation (EI) and firm performance (FP) is central to environmental management research, yet empirical evidence remains fragmented and highly context dependent. This article presents a global systematic literature review (SLR) of 541 empirical studies (2006–April 2025) to (i) diagnose the systematic sources of ...
Ali Mammadov
wiley   +1 more source

Free Convection Flow and Heat Transfer of Tangent Hyperbolic past a Vertical Porous Plate with Partial Slip

open access: yesJournal of Applied Fluid Mechanics, 2016
This article presents the nonlinear free convection boundary layer flow and heat transfer of an incompressible Tangent Hyperbolic non-Newtonian fluid from a vertical porous plate with velocity slip and thermal jump effects.
V. Ramachandra Prasad   +2 more
doaj  

When the Remedy Is Worse Than the Illness: Carbon Performance and Growth Opportunities Under the EU ETS

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This paper examines how the European Union Emissions Trading System allowance prices reshape the link between corporate environmental performance (CEP) and firms' growth expectations, measured by Tobin's Q. Using a panel of 1370 listed firms across 15 European countries from 2005 to 2024 and high‐dimensional fixed‐effects models, we first ...
Adrián Ferreras
wiley   +1 more source

Innovation Pathways to Carbon Efficiency: Disentangling the Effects of AI, R&D, and Clean Energy Blessings on U.S. Environmental Sustainability

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The United States (U.S.) faces challenges in achieving its ambitious net‐zero carbon emissions target by 2050, with current emissions having fallen by less than 1% in 2024. Despite an investment of $500 billion in low‐carbon resources while holding the second‐largest green technology patent portfolio globally, it is further imperative to ...
Md Zubair Ahmad   +5 more
wiley   +1 more source

Cluster Analysis of Circular Economy and Industrial Symbiosis Practices and Their Impact on Sustainability Performance in the Plastics Industry

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines how plastics manufacturing firms can be classified according to their level of implementation of circular economy (CE) and industrial symbiosis (IS) practices and how such adoption influences sustainability performance. Using data from plastics manufacturing firms, we integrate cluster analysis with partial least squares ...
Laura Cristina Ramírez‐Rodríguez   +3 more
wiley   +1 more source

Nonlinear second order parabolic and hyperbolic equations: Blow up and asymptotic behavior of solutions

open access: yes, 2020
In this thesis blow up in a finite time and asymptotic behavior of solutions of initial boundary value problems for second order nonlinear parabolic and hyperbolic equations are studied. Sufficient conditions for blow up of solutions of initial boundary value problems for nonlinear non-autonomous parabolic and damped hyperbolic equations under Robin ...
openaire   +1 more source

Frugal Innovation as a Strategic Mechanism Linking Learning, International Growth Orientation, and Performance

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines how international growth orientation and organizational learning capability jointly influence frugal innovation and organizational performance. Survey data were collected from 342 manufacturing firms in Santa Catarina (Southern Brazil) and analyzed using partial least squares structural equation modeling and multigroup ...
Júlia Quintino Sant'Ana   +3 more
wiley   +1 more source

Orchestrating Ecosystem Resources for Sustainability: Coopetition, Digital Transformation, and Disruptive Sustainable Innovation

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT As sustainability transitions accelerate, firms increasingly engage in innovation ecosystems to pursue disruptive sustainable innovation (DSI). Nevertheless, empirical understanding regarding how innovation ecosystem coopetition—simultaneous cooperation and competition among interdependent actors—translates into sustainability‐oriented ...
Jin‐Sup Jung, Min‐Jae Lee
wiley   +1 more source

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