Results 111 to 120 of about 2,522,578 (311)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Positive Solutions for Systems of Second-Order Difference Equations
Discrete Dynamics in Nature and Society, 2015 We study the existence and nonexistence of positive solutions of some systems of nonlinear second-order difference equations subject to multipoint boundary conditions which contain some positive constants.
Johnny Henderson, Rodica Luca
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Finite element solutions to boundary value problems
, 1976 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis consists of two distinct parts which deal with two-point boundary value problems and parabolic problems, respectively.
Moore, P
core
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
ActuatorsThis paper presents an observer-based dynamic output-feedback controller design procedure using linear matrix inequality (LMI) optimization for second-order systems with uncertainty and persistent perturbation in the states.
Danielle Gontijo +3 more
doaj +1 more source
Second-order terminal sliding mode control of uncertain multivariable systems
, 2007 A second-order terminal sliding mode controller for uncertain multivariable systems is proposed in this paper. The controller adopts the hierarchical control structure.
X Han (2570758) +2 more
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Subharmonic solutions for nonautonomous second-order Hamiltonian systems
Electronic Journal of Differential Equations, 2012 In this article, we prove the existence of subharmonic solutions for the non-autonomous second-order Hamiltonian system $ddot{u}(t)+V'(t,u(t))=0$. Also we study the minimality of their periods, when the nonlinearity $V'(t,x)$ grows faster than $|x ...
Mohsen Timoumi
doaj