Results 101 to 110 of about 3,330,187 (282)
Plato on Coming-to-Be: A Midway Path between Eleaticism and Creationism
The Parmenides is the locus of Plato’s theoria motus abstracti (that is, abstract kinematics) for it is here that Plato gives a mereological and locational analysis of motion (First Deduction: 138b7-139b3) and discusses the famous puzzle of the instant ...
Florian Marion
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Global Market for Liquefied Natural Gas [PDF]
Liquefied natural gas (LNG) provides an economic means to transport natural gas over long distances, bringing production from remote gas reserves to market.
David Jacobs
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Horizon of the End. Opinions on The Second Coming by William Butler Yeats
The outline presents a comprehensive interpretation of the poem The Second Coming by William Butler Yeats.
Paweł Próchniak
doaj
Inventing a Testimony (Chapter 18 of Jesus Girls: True Tales of Growing Up Female and Evangelical)
Excerpt: Several months into my first year of college, I realized there was an optional worship service for students every Sunday evening and that anyone who wanted to be considered a Christian by her peers had better show up.
Mock, Melanie Springer
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

