Results 111 to 120 of about 399,825 (296)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
William Butler Yeats’ “The Second Coming” A Stylistic Analysis [PDF]
, 2016 The aim of this present paper is to analyze William Butler Yeats’ Poem ‘The second coming’ from the stylistic analysis perspective. The stylistic analysis envisaged here views the poem as a linguistic construct in terms of phonological, lexical ...
Khader, Khader T.
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Staying in, tuning in, and coming out: Music as imagined space in lesbians’ coming out geographies
, 2012 This thesis examines the mutually constitutive relationship between lesbians, music, place and space. It is argued that music creates safe spaces for a small group of lesbians during their coming out process.
Hardie, Lisa Caroline
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Coming Again! Global Views on the Second Coming of Jesus
, 2019 In spite of this strong agreement among members worldwide that the Second Coming is near, when members were asked to respond to the statement, “I am confident that Jesus Christ will return in my lifetime” (Q42.21), the answers were surprisingly different.
Činčala, Petr A
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Jesus’ Second Coming in a Fatwā by al-Suyūṭī
, 2021 The essay aims at analyzing a relatively short fatwā on Jesus’ second coming on earth: Kitāb al-i‘lām bi-ḥukm ‘Īsā ‘alayhi al-salām (The Book of Declaration of Jesus’ Judgement, Peace Be Upon Him).
antonio cuciniello
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