Results 131 to 140 of about 399,825 (296)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

[AT&T riders coming into the second LSRFA pit-stop]

, 2011
Photograph of riders coming up to the second LSRFA pit-stop. In the front are three AT&T group members and three other riders are following behind them.

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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Deliberate self-harm and suicide in people with immigrant background: how can reason for immigration and country of origin differentiate the risks?

European Psychiatry
Introduction A growing body of research have devoted into suicide and deliberate self-harm in immigrant population, but no study has examined how reason for immigrating to the host country differentiates the risks.
P. Qin
doaj   +1 more source

What Will Happen at the Second Coming of Christ?

, 1981
These are the sermon notes for the sermon, What Will Happen at the Second Coming of Christ?, by Dr. W.O. Vaught, who was the pastor of the Immanuel Baptist Church in Little Rock, AR.
Vaught, W. O.
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Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

C. S. Lewis's Escatology (1) : On the doctrine of the Second Coming

, 2001
P(論文)This study is a step to a systematic presentation of C. S. Lewis's Escatology. In this paper, however, I confined myself to the doctrine of the Second Coming discussed in Lewis's 'The World's Last Night.' In part I, I made a brief survey of ...
9000002543387, TAKENO, Kazuo, 竹野, 一雄, タケノ, カズオ, 1647   +4 more
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The expectation of the second coming (parousia) of Jesus Christ in early Christianity

, 2023
"Erken Dönem Hıristiyanlıkta Mesih İsa'nın İkinci Gelişi (Parousia) Beklentisi" başlıklı tezimiz, giriş ve üç bölümden oluşmaktadır. Girişte önce araştırmanın konusu, önemi, amacı, kapsamı, sınırlılıkları ve yöntemi gibi hususlar hakkında bilgilendirme ...
Gören, Arif
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Coming of age in Second Life : an anthropologist explores the virtually human

, 2009
Coming of age in Second Life : an anthropologist explores the virtually ...
Tanya King (13097013), Ian Warren (13074192)   +1 more
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