Results 91 to 100 of about 17,928,638 (295)
A second derivative SQP method: Theoretical issues
, 2016 Sequential quadratic programming (SQP) methods form a class of highly efficient algorithms for solving nonlinearly constrained optimization problems. Although second derivative information may often be calculated, there is little practical theory that justifies exact-Hessian SQP methods.
Gould, N, Robinson, D
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Catalogue of the Second District Agricultural School
, 1914 This document is a catalog for the Second District Agricultural School in Evergreen, Alabama.
Second District Agricultural School
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A new method to compute second derivatives
Journal of Computer Science and Technology, 2001 Facultad de ...
Scolnik, Hugo Daniel +1 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 1980 Physicochemical Methods for Water and Wastewater Treatment covers the proceedings of the Second International Conference held in Lublin in June 1979. The papers in this compendium discuss scientific findings on how to treat water and wastewater using ...
International Conference on Physicochemical Methods for Water and Wastewater Treatment < 1979, Lublin, Poland> +1 more
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A general semilocal convergence result for Newton's method under centered conditions for the second derivative [PDF]
, 2012 From Kantorovich’s theory we present a semilocal convergence result for Newton’s method which is based mainly on a modification of the condition required to the second derivative of the operator involved.
Hernández, Miguel Ángel +8 more
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Second derivative block methods for solving first and higher order ordinary differential equations [PDF]
, 2018 Traditionally, higher order ordinary differential equations (ODEs) are solved by reducing them to an equivalent system of first order ODEs. However, it is more cost effective if they can be solved directly by numerical methods.
Turki, Mohammed Yousif
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source