Results 101 to 110 of about 1,279,657 (325)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Detection of SPAD Content in Leaves of Grey Jujube Based on Near Infrared Spectroscopy
HorticulturaeThe efficient and non-destructive inspection of the chlorophyll content of grey jujube leaf is of great significance for its growth surveillance and nutritional diagnosis. Near-infrared spectroscopy combined with chemometric methods provides an effective
Lanfei Wang +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Journal of Spectroscopy, 2013 Two simple and selective methods were developed for the simultaneous determination of tenofovir fumarate (TEN) and emtricitabine (EMT) in combined tablets.
Mohammad H. AbdelHay +3 more
doaj +1 more source
Second Derivative Mono-Implicit Runge-Kutta Methods
Earthline Journal of Mathematical SciencesMono-implicit Runge-Kutta (MIRK) methods are Runge-Kutta methods having its stages depending on its output. In this paper, we develop a family of second derivative mono-implicit Runge-Kutta (SDMIRK) methods for the numerical solution of stiff initial value problems (IVPs) in ordinary differential equations (ODEs).
A. G. Ariwayo +2 more
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A Class of Two-Derivative Two-Step Runge-Kutta Methods for Non-Stiff ODEs
Journal of Applied Mathematics, 2019 In this paper, a new class of two-derivative two-step Runge-Kutta (TDTSRK) methods for the numerical solution of non-stiff initial value problems (IVPs) in ordinary differential equation (ODEs) is considered.
I. B. Aiguobasimwin, R. I. Okuonghae
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source