Results 81 to 90 of about 12,779,859 (228)

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu, Changgeng Song, Dianwei Wu, Xiaoqian Niu, Jianmin Hao, Lijuan Liu, Xiaogang Kang, Wen Jiang   +7 more
wiley   +1 more source

Data-Driven Ship Parametric Rolling Prediction: LightGBM Modeling and SHAP-Based Interpretability Analysis

Journal of Marine Science and Engineering
Within the framework of the International Maritime Organization (IMO) Second-Generation Intact Stability Criteria, parametric roll (PR) is recognized as an important dynamic stability failure mode that may occur when ships operate in waves.
Qiang Sun, Yupeng Wang, Yaohua Zhou
doaj   +1 more source

Second Generation Intact Stability criteria: Analysis, Implementation and Applications to significant ship typologies

, 2019
The following doctoral thesis addresses all the stability failures embraced by the Second-Generation Intact Stability criteria (SGISc). These criteria are under finalization within the sub-Committee at the International Maritime Organization (IMO ...
PETACCO, NICOLA
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Stochastic stability analysis of ship rolling based on first-passage probability

Zhongguo Jianchuan Yanjiu
ObjectiveParametric rolling is a typical mode of dynamic instability, characterized by strong nonlinear dynamics and random wave excitation forces.International maritime organization (IMO) has issued the "Guidelines for assessment of the second ...
Yaliu LIU, Jiarun ZHANG, Shuxia BU, Min GU, Liqin LIU   +4 more
doaj   +1 more source

EVALUATION OF IMO SECOND GENERATION INTACT STABILITY CRITERIA

, 2013
Vessels must have sufficient stability in order to sail safely. Vessels need to provide necessary stability criteria during entire voyage. First international stability regulations have been applied to vessels in 1968.
YILMAZ, Hüseyin, YILDIZ, Burak
core  

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

CFD simulation and analysis of surf-riding motion of the ONR tumblehome ship using a body-force method

Zhongguo Jianchuan Yanjiu
ObjectiveFollowing the formal release of the interim guidelines on the second-generation intact stability criteria (SGISc) by the international maritime organization (IMO) in 2020, the research focus has shifted from vulnerability criteria to direct ...
Ke ZENG, Jiang LU
doaj   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son, Inyoung Hwang, Sang Won Lee, Yun Kim   +3 more
wiley   +1 more source

Real-time evaluation of second generation intact stability criteria

, 2016
The performance of a vessel cannot solely be determined as a function of its size, speed and autonomy. The seakeeping behaviour of the vessel in extreme weather conditions is very difficult to predict and the IMO is in the process of introducing new ...
Laurens, J. M., Ariffin, A., Mansor, S.
core