Results 101 to 110 of about 7,071,070 (299)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A Note On The Characterization Of Inefficiency In Stochastic Overlapping Generations Economies [PDF]
In this paper, we provide a characterization of interim ine±ciency in stochastic economies of overlapping generations under possibly sequentially incomplete markets.
Gaetano Bloise, Filippo L. Calciano
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Local indeterminacy in two-sector overlapping generations models [PDF]
In this paper, we consider a two-sector two-periods overlapping generations model with inelastic labor, consumption in both periods of life and homothetic CES preferences.
Alain Venditti, Carine Nourry
core
Prior research has found that immigrants are often overeducated: their educational attainment is higher than required or commonly observed in their occupation.
Weber, Rosa +2 more
core +1 more source
The Complexity of Immigrant Generations: Implications for Assessing the Socioeconomic Integration of Hispanics and Asians [PDF]
Much of the socioeconomic mobility achieved by U.S. immigrant families takes place across rather than within generations. When assessing the long-term integration of immigrants, it is therefore important to analyze differences not just between the ...
Brian Duncan, Stephen J. Trejo
core +2 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Prolonged grief among Turkish migrants in Germany: prevalence and the role of migratory grief
European Journal of PsychotraumatologyBackground: Prolonged grief disorder (PGD) is associated with negative health outcomes and appears to be more prevalent among migrants. For migrants, bereavement also includes losses tied to their country of origin, leading to migratory grief.
Viktoria Schmidt +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source