Results 31 to 40 of about 852,308 (302)

Excavations of a second iron age enclosure on\ud Winnall Down, Winchester, Hampshire, 2006 [PDF]

open access: yes, 2014
Aerial survey during the 1970s identified two\ud plough-levelled enclosures, 300m apart, on Winnall\ud Down, Winchester. One of these, Winnall Down I,\ud was excavated by Fasham (1985) in advance of\ud the M3 motorway extension, and revealed evidence\ud for intensive Bronze Age and Iron Age occupation.\ud The adjacent enclosure, Winnall Down II, was ...
Davis, Oliver   +3 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mechanical Properties and Microstructure Analysis of Cement Mortar Mixed with Iron Ore Tailings

open access: yesBuildings, 2023
In order to study the feasibility and sand substitution mechanism of cement mortar mixed with iron ore tailings (IOT), iron ore tailings cement mortars (referred to as IOTC) with IOT content of 0%, 25%, and 50% were made and tested.
Junsheng Li   +5 more
semanticscholar   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Pengaruh suplementasi tablet Fe dengan supervisi suami pada ibu hamil terhadap umur kehamilan di Kabupaten Bantul

open access: yesJurnal Gizi Klinik Indonesia, 2005
Background: The high prevalence of anemia pregnant women anemia in Indonesia reaches 50%–70%, and it is caused by many factors. First, it may be caused by low compliance of iron supplementation and second, it may be caused by bad distribution of iron ...
Dhuto Widagdo   +2 more
doaj   +1 more source

Prevalence & risk factors for iron deficiency anemia among pregnant women attending antenatal care clinics in Qena city

open access: yesSVU - International Journal of Medical Sciences, 2023
Background: Iron deficiency anemia (IDA) during pregnancy is a universal public health problem. There is geographical variation in the prevalence and risk factors.
Mohammad AM Ahmed *   +3 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

Iron deficiency and the effectiveness of the BNT162b2 vaccine for SARS-CoV-2 infection: A retrospective, longitudinal analysis of real-world data.

open access: yesPLoS ONE, 2023
BackgroundIron plays a key role in human immune responses; however, the influence of iron deficiency on the coronavirus disease 2019 (COVID-19) vaccine effectiveness is unclear.AimTo assess the effectiveness of the BNT162b2 messenger RNA COVID-19 vaccine
Lilac Tene   +7 more
doaj   +1 more source

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