Results 41 to 50 of about 5,007,076 (313)

Varying c and Particle Horizons [PDF]

open access: yes, 2001
We explore what restrictions may impose the second law of thermodynamics on varying speed of light theories. We find that the attractor scenario solving the flatness problem is consistent with the generalized second law at late time.Comment: Latex file ...
Albrecht   +33 more
core   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A Kinetic Perspective on k - ϵ Turbulence Model and Corresponding Entropy Production

open access: yesEntropy, 2016
In this paper, we present an alternative derivation of the entropy production in turbulent flows, based on a formal analogy with the kinetic theory of rarefied gas.
Pietro Asinari   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

MHD Free Convection and Entropy Generation in a Corrugated Cavity Filled with a Porous Medium Saturated with Nanofluids

open access: yesEntropy, 2018
MHD free convection inside a triangular-wave-shaped corrugated porous cavity with Cu-water nanofluid is numerically studied with the finite element method. The influences of the Grashof number ( 10 4 ≤ Gr ≤ 10 6 ), Hartmann number (
Ali J. Chamkha, Fatih Selimefendigil
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Exergy-Based Efficiency Assessment of Fans vs. Isentropic Efficiency

open access: yesInternational Journal of Turbomachinery, Propulsion and Power, 2023
The efficiency definition allows us to compare two machines with each other. In general, the efficiency is defined as the ratio of usable power to the required power. This raises the question: what is the usable power?
Johannes Brötz   +2 more
doaj   +1 more source

Gravitational Entropy and the Second Law of Thermodynamics [PDF]

open access: yes, 2014
The spontaneous violation of Lorentz and diffeomorphism invariance in a phase near the big bang lowers the entropy, allowing for an arrow of time and the second law of thermodynamics.
Moffat, J. W.
core   +3 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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