Results 61 to 70 of about 825,806 (292)

Second primary neoplasms in 633,964 cancer patients in Sweden, 1958-1996 [PDF]

International Journal of Cancer, 2001
The Swedish Family-Cancer Database was used to analyze concordant (same site) and discordant (different site) second primary neoplasms in 633,964 cancer patients diagnosed from 1958 to 1996. Cases of second malignant neoplasms were extracted from the Database if the diagnosis date of the first and second cancer differed by at least 1 month.
C, Dong, K, Hemminki
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Prevalence of Transcriptionally Active HPV Infection in Tumor-Free Oropharyngeal Tissue of OPSCC-Patients

Frontiers in Oncology, 2022
ObjectivesThe natural history of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) is still largely unknown. Since reports of second primary tumors (SPTs) in patients with HPV-related OPSCCs are increasing, a multifocal HPV infection, hinting a ...
Vittoria Guarda, Lea Schroeder, Michael Pawlita, Kristian Ikenberg, Niels J. Rupp, Wolfram Jochum, Sandro J. Stoeckli, Dana Holzinger, Martina A. Broglie   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Secondary Primary Neoplasms in Survivors of Wilms Tumour - A Population-based Cohort Study from the British Childhood Cancer Survivor Study

, 2008
A British population-based cohort study was carried out to determine the risk of second primary neoplasms in survivors of Wilms' tumour. The cohort was obtained from the British Childhood Cancer Survivor Study, a population-based cohort study of ...
Lancashire, Emma, Pritchard-Jones, K, Winter, David, Stiller, CA, Frobisher, Clare; id_orcid, Reulen, Raoul; id_orcid, Hawkins, Michael, Taylor, Aliki   +7 more
core   +1 more source

Preoperative Short-Course Radiotherapy and Surgery versus Surgery Alone for Patients with Rectal Cancer: A Propensity Score-Matched Analysis at 18-Year Follow-Up

Biomedicines, 2021
A significant problem for long-term rectal cancer survivors may be the late toxicity of radiotherapy. It creates the possible risk of developing second primary malignancy and a theoretical decrease in overall survival.
Radoslaw Pach, Piotr Richter, Marek Sierzega, Natalia Papp, Antoni Szczepanik   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Second malignant neoplasms in operable carcinoma of the breast

, 1984
Development of a second malignant neoplasm (SMN) following prolonged cytotoxic therapy is a potential delayed consequence of tumor treatment [1, 5, 6, 20, 26, 27, 31, 34, 46, 48, 49, 51].
Nissen-Meyer, R, Jones, S E; id_orcid, Bonadonna, G, Holdener, E E, Rubens, R, Senn, H J, Howell, A; id_orcid   +6 more
core   +3 more sources

Clinical Analysis of 120 Cases of Multiple Primary Malignant Neoplasms

Zhongliu Fangzhi Yanjiu, 2019
Objective To explore the etiology, clinical features, treatment and prognosis of multiple primary malignant neoplasms. Methods The medical records of 120 patients with multiple primary malignant neoplasms in Dongzhimen Hospital Affiliated to Beijing ...
ZHANG Zhichun, JIA Mengran, DING Hao, FAN Qiuyue, TIAN Shaodan   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source